Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548423 | 0.93 | PPARG (0.63) | PPARGABCG2ADORA3ABCB1KDM4E | |
| SCHEMBL7549118 | 0.84 | PPARG (0.54) | PPARGABCG2ADORA3EDNRA | |
| SCHEMBL30375357 | 0.83 | PPARG (0.77) | PPARGABCG2ADORA3ABCB1KDM4E | |
| SCHEMBL1765292 | 0.82 | ADORA3 (0.67) | PPARGABCG2ADORA3ABCB1KDM4E | |
| SCHEMBL1483627 | 0.81 | PPARG (0.67) | PPARGABCG2ADORA3ABCB1KDM4E | |
| Water SCHEMBL4628870 | 0.81 | ADORA3 (0.66) | PPARGABCG2ADORA3ABCB1KDM4E | |
| SCHEMBL7948858 | 0.81 | PPARG (0.67) | PPARGABCG2ADORA3ABCB1KDM4E | |
| SCHEMBL7551823 | 0.81 | PPARG (0.92) | PPARGABCG2ADORA3ABCB1KDM4E | |
| SCHEMBL1664326 | 0.79 | ADORA3 (0.70) | PPARGABCG2ADORA3ABCB1KDM4E | |
| SCHEMBL15270283 | 0.78 | PPARG (0.44) | PPARGABCB1MAPTEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214308-A2 | NOVEL FLAVONOIDS | VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDERWIJS (NL) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021608-A2 | NOVEL FLAVONOIDS | VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDERWIJS (NL) | 2001-03-29 | — | — | WO | disclosed |