SCHEMBL774317

SCHEMBL774317

COc1cc2oc(-c3ccccc3)c(OC)c(=O)c2c(OC)c1OC

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 3/20 0.72
ABCB1 P08183 2/20 0.64
ABCG2 Q9UNQ0 3/20 0.63
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
KDM4E B2RXH2 3/20 0.59
ALDH1A1 P00352 3/20 0.59
CYP3A4 P08684 3/20 0.59
HSD17B10 Q99714 3/20 0.59
CYP2C9 P11712 2/20 0.59
MAPK1 P28482 1/20 0.59
SLC22A2 O15244 1/20 0.59
SLC22A1 O15245 1/20 0.59
MAPT P10636 3/20 0.57
POLB P06746 1/20 0.57
HPGD P15428 2/20 0.56
THRB P10828 1/20 0.56
MAOA P21397 1/20 0.56
CYP2D6 P10635 1/20 0.56
TSHR P16473 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10646756 0.90 ADORA3 (0.60) ADORA3ABCB1ABCG2MEN1KMT2A
SCHEMBL737207 0.89 ADORA3 (0.58) ADORA3ABCB1ABCG2MEN1KMT2A
SCHEMBL28066116 0.88 MKNK2 (0.63) ADORA3ABCB1ABCG2MEN1KMT2A
SCHEMBL28647308 0.88 ABCB1 (0.81) ADORA3ABCB1ABCG2MEN1KMT2A
SCHEMBL4277299 0.88 ADORA3 (0.76) ADORA3ABCB1ABCG2MEN1KMT2A
SCHEMBL16894654 0.87 ADORA3 (0.72) ADORA3ABCB1ABCG2MEN1KMT2A
SCHEMBL31287150 0.87 ADORA3 (0.72) ADORA3ABCB1ABCG2MEN1KMT2A
SCHEMBL2727281 0.86 ABCG2 (0.83) ADORA3ABCB1ABCG2MEN1KMT2A
SCHEMBL4124452 0.86 ABCB1 (0.63) ADORA3ABCB1ABCG2MEN1KMT2A
SCHEMBL1765292 0.86 ADORA3 (0.67) ADORA3ABCB1ABCG2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117969715-A Qualitative and quantitative detection method for bioactive substances with different structures in agricultural products 上海市农业科学院 2024-05-03 CN claimed
CN-116268070-A Polyphenol additive capable of improving frozen storage quality of non-rinsed minced fillet and application thereof 中南林业科技大学 2023-06-23 CN claimed
CN-109662984-B Application of laggera pterodonta and rosemary extract in medicine for resisting type II dengue virus 昆明医科大学 2022-07-26 CN claimed
CN-114031951-A Purple bamboo and plum purple red pigment powder and preparation method and application thereof 天津工业大学 2022-02-11 CN claimed
CN-109374762-B Method for identifying citrus reticulata blanco and citrus reticulata blanco varieties based on metabonomics 广州中医药大学第一附属医院 2021-10-08 CN claimed
CN-110038054-A Active component improves sleep or antidepression or improves in failure of memory drug or food and applies in preparation in gardenia and branches and leaves fruit 江西中医药大学 2019-07-23 CN claimed
CN-107411083-A Cape jasmine alcohol elution auxiliary improvement of memory capsule or tablet are applied in auxiliary improving memory function health food is prepared 江西中医药大学 2017-12-01 CN claimed
EP-2544554-B1 METHOD FOR STABILIZING WATER INSOLUBLE BIOACTIVE COMPOUND AQUEOUS DISPERSIONS STOKELY VAN CAMP INC (US) 2016-11-30 EP claimed
US-8945646-B2 Method for manufacturing polymethoxyflavones that are highly stable over time and have reduced residual pesticide levels OGAWA & CO., LTD. (JP) 2015-02-03 US claimed
EP-2785204-A1 ZERO CALORIE POLYPHENOL AQUEOUS DISPERSIONS Pepsico, Inc. (US) 2014-10-08 EP claimed
CN-100389784-C Application of effective part and effective component of Achillea alpina to anti-anaphylactic reaction ABE SLAV (CN) 2008-05-28 CN claimed
WO-2007070986-A1 FLAVONES ECOBIOTICS LIMITED (AU) 2007-06-28 WO claimed
CN-1788742-A Application of effective part and effective component of Achillea alpina to anti-anaphylactic reaction SLAV ABE (CN) 2006-06-21 CN claimed
EP-0605261-B1 Use of a flavone derivative as taste modifier and a method of modifying taste SAN EI GEN FFI INC (JP) 1999-09-15 EP claimed
EP-0915864-A1 GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE Dong A Pharmaceutical Co. Ltd. (KR) 1999-05-19 EP claimed
EP-0885192-A1 DIHYDROPYRIDINE-, PYRIDINE-, BENZOPYRAN- ONE- AND TRIAZOLOQUINAZOLINE DERIVATIVE, THEIR PREPARATION AND THEIR USE AS ADENOSINE RECEPTOR ANTAGONISTS THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) 1998-12-23 EP claimed
WO-1998004541-A1 GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE DONG A PHARMACEUTICAL CO., LTD. (KR) 1998-02-05 WO claimed
WO-1997027177-A2 DIHYDROPYRIDINE-, PYRIDINE-, BENZOPYRAN-4-ONE- AND TRIAZOLOQUINAZOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ADENOSINE RECEPTOR ANTAGONISTS THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1997-07-31 WO claimed
CN-1033365-C Composition based on hydrate lamellar lipides or liposomes, containing extract of scutellaria, or at least component thereof, and cosmeties or pharmaceutical, especially having anti-allergic,......... LVMH RECH (FR) 1996-11-27 CN claimed
CN-1037834-A With hydration lamellar fat mutually or liposome is the compositions of main component, wherein contain the Radix Scutellariae extract or contain wherein a kind of component at least, and cosmetics or medicament, especially skin is had antiallergic, the compositions of antiinflammatory or defying age performance LVMH RECH (FR) 1989-12-13 CN claimed