SCHEMBL17655006

SCHEMBL17655006

Fc1cc(OC(F)(F)c2c(F)cc(-c3ccc(CCCCC4CCCC4)cc3)cc2F)cc(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
MOGAT2 Q3SYC2 2/20 0.34
F10 P00742 1/20 0.31
SPHK1 Q9NYA1 2/20 0.31
RARB P10826 2/20 0.31
RARA P10276 1/20 0.31
RARG P13631 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
HTR1A P08908 1/20 0.30
HTR1D P28221 1/20 0.30
HTR1B P28222 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17655005 0.97 MOGAT2 (0.36) PPARGPPARAMOGAT2F10HRH3
SCHEMBL16978487 0.92 F10 (0.32) MOGAT2F10
SCHEMBL17070199 0.91 F10 (0.32) PPARGPPARAMOGAT2F10
SCHEMBL17827775 0.88 GPR84 (0.35) F10HRH3
SCHEMBL17655002 0.87 HTR1A (0.38) RARBRARAHRH3TDP1HTR1A
SCHEMBL17070271 0.87 RARB (0.32) RARBRARARARGHRH3
SCHEMBL16978492 0.86 LTA4H (0.33) F10HRH3
SCHEMBL17655004 0.86 HRH3 (0.40) RARBRARAHRH3TDP1HTR1A
SCHEMBL17070269 0.84 GPR84 (0.31)
SCHEMBL17070273 0.84 GPR84 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9303208-B2 Liquid crystal compound containing cyclopentyl and difluorometheneoxy linking group, preparation method and application thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) 2016-04-05 US disclosed