SCHEMBL17655893

SCHEMBL17655893

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5cccc(-c6ccc(-n7cnc8ccccc87)cc6)c45)cc3)n2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.60
KMT2A Q03164 3/20 0.60
NPSR1 Q6W5P4 3/20 0.60
PTK2B Q14289 1/20 0.60
HTT P42858 5/20 0.54
CYP1A2 P05177 2/20 0.52
CYP2C9 P11712 2/20 0.52
CYP2C19 P33261 2/20 0.52
POLB P06746 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
THRB P10828 1/20 0.52
PPP1CA P62136 1/20 0.49
FGFR1 P11362 2/20 0.49
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PDE2A O00408 1/20 0.43
PDE3B Q13370 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17655803 0.93 MAPT (0.62) MAPTKMT2ANPSR1PTK2BHTT
SCHEMBL17655892 0.93 MAPT (0.62) MAPTKMT2ANPSR1PTK2BHTT
SCHEMBL17655958 0.87 KDR (0.55) MAPTKMT2ANPSR1PTK2BHTT
SCHEMBL17655894 0.85 MAPT (0.55) MAPTKMT2ANPSR1PTK2BHTT
SCHEMBL17655881 0.85 MAPT (0.55) MAPTKMT2ANPSR1PTK2BHTT
SCHEMBL17656047 0.82 KDR (0.52) MAPTKMT2ANPSR1PTK2BHTT
SCHEMBL17655834 0.82 KDR (0.52) MAPTKMT2ANPSR1PTK2BHTT
SCHEMBL17655875 0.80 MAPT (0.57) MAPTKMT2ANPSR1PTK2BHTT
SCHEMBL17655826 0.80 MAPT (0.57) MAPTKMT2ANPSR1PTK2BHTT
SCHEMBL17655882 0.80 MAPT (0.57) MAPTKMT2ANPSR1PTK2BHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3002282-B1 HETERO RING COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEMICAL LTD (KR) 2019-01-02 EP disclosed
US-9882145-B2 Hetero ring compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2018-01-30 US disclosed
US-9882145-B2 Hetero ring compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2018-01-30 US disclosed
US-20160141514-A1 HETERO RING COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2016-05-19 US disclosed
US-20160141514-A1 HETERO RING COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2016-05-19 US disclosed
EP-3002282-A1 HETERO RING COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG Chem, Ltd. (KR) 2016-04-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160141514-A1 HETERO RING COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME CRY1, CRY2, PER2 MAPT 329/4885KMT2A 530/4885NPSR1 4645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.