Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.30 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2235412 | 0.69 | PKM (0.42) | PKMALDH1A1CYP3A4BAZ2BKMT2A | |
| SCHEMBL334557 | 0.66 | — | — | |
| SCHEMBL18258623 | 0.66 | PKM (0.42) | PKMALDH1A1CYP3A4BAZ2BKMT2A | |
| SCHEMBL26725037 | 0.66 | ALDH1A1 (0.41) | PKMALDH1A1KMT2ARAB9AHPGD | |
| SCHEMBL18258626 | 0.66 | PKM (0.42) | PKMALDH1A1CYP3A4BAZ2BKMT2A | |
| SCHEMBL28311572 | 0.65 | — | — | |
| SCHEMBL9918671 | 0.65 | — | — | |
| SCHEMBL27594334 | 0.64 | PKM (0.41) | PKMALDH1A1CYP3A4BAZ2BKMT2A | |
| SCHEMBL4583848 | 0.63 | PTGS2 (0.40) | CYP3A4BAZ2BKMT2ARAB9AKCNJ1 | |
| SCHEMBL13539050 | 0.62 | PKM (0.42) | PKMALDH1A1CYP3A4BAZ2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002283-A1 | THIAZOLE DERIVATIVES | Kyowa Hakko Kirin Co., Ltd. (JP) | 2016-04-06 | — | — | EP | disclosed |