Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21169639 | 0.81 | RORC (0.30) | RORC | |
| SCHEMBL17656944 | 0.75 | DRD2 (0.40) | RORCDRD2DRD1 | |
| SCHEMBL17660751 | 0.74 | DRD2 (0.40) | RORCDRD2DRD1 | |
| SCHEMBL17664732 | 0.72 | — | — | |
| SCHEMBL17660405 | 0.71 | — | — | |
| SCHEMBL21169638 | 0.67 | MAPT (0.45) | — | |
| SCHEMBL31137696 | 0.63 | DRD2 (0.43) | RORCDRD2DRD1 | |
| SCHEMBL5078226 | 0.61 | CYP2C19 (0.41) | — | |
| SCHEMBL1097170 | 0.61 | CYP2C19 (0.41) | — | |
| SCHEMBL22375179 | 0.60 | CYP2C9 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10829455-B2 | Methods of resolving racemic mixture to obtain (−)-Huperzine A | AMPHASTAR NANJING PHARMACEUTICALS INC (CN) | 2020-11-10 | — | — | US | disclosed |
| US-20190210972-A1 | METHODS OF RESOLVING RACEMIC MIXTURE TO OBTAIN (-)-HUPERZINE A | AMPHASTAR NANJING PHARMACEUTICALS INC (CN) | 2019-07-11 | — | — | US | disclosed |
| US-10287249-B2 | Methods of resolving racemic mixture to obtain (−)-huperzine A | AMPHASTAR PHARMACEUTICALS, INC. (US) | 2019-05-14 | — | — | US | disclosed |
| WO-2016054286-A1 | METHODS OF RESOLVING RACEMIC MIXTURE TO OBTAIN (-)-HUPERZINE A | AMPHASTAR PHARMACEUTICALS, INC. (US) | 2016-04-07 | — | — | WO | disclosed |
| US-20160096808-A1 | METHODS OF RESOLVING RACEMIC MIXTURE TO OBTAIN (-)-HUPERZINE A | AMPHASTAR NANJING PHARMACEUTICALS INC. (CN) | 2016-04-07 | — | — | US | disclosed |
| US-20160096808-A1 | METHODS OF RESOLVING RACEMIC MIXTURE TO OBTAIN (-)-HUPERZINE A | AMPHASTAR NANJING PHARMACEUTICALS INC. (CN) | 2016-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10829455-B2 | Methods of resolving racemic mixture to obtain (−)-Huperzine A | ADH1C, GALE, UGT8 | RORC 2302/4885DRD2 1095/4885DRD1 1121/4885 |
| US-20190210972-A1 | METHODS OF RESOLVING RACEMIC MIXTURE TO OBTAIN (-)-HUPERZINE A | ADH1C, GALE, UGT8 | RORC 2311/4885DRD2 1155/4885DRD1 1140/4885 |
| US-10287249-B2 | Methods of resolving racemic mixture to obtain (−)-huperzine A | ADH1C, GALE, UGT8 | RORC 2302/4885DRD2 1095/4885DRD1 1121/4885 |
| US-20160096808-A1 | METHODS OF RESOLVING RACEMIC MIXTURE TO OBTAIN (-)-HUPERZINE A | ADH1C, GALE, UGT8 | RORC 2311/4885DRD2 1155/4885DRD1 1140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.