SCHEMBL17657147

SCHEMBL17657147

c1ccc(-c2ccc(N(c3ccc4c(c3)N(c3ccccc3)c3ccccc3C4(c3ccccc3)c3ccccc3)c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-4)cc2)cc1

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
OPRK1 P41145 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PDE6D O43924 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17657135 0.97 PDK2 (0.33) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL20318579 0.96 PDK2 (0.32) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL20318583 0.96 PDK2 (0.32) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL17657211 0.95 PDK2 (0.30) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL17657209 0.94 KDM4E (0.33) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL17657140 0.94 PDK2 (0.31) PDK2PDE6D
SCHEMBL17657124 0.94 PGR (0.32)
SCHEMBL22596254 0.94 PDK2 (0.31) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL17657131 0.93
SCHEMBL22596237 0.93 PDK2 (0.33) PDK2KDM4EMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9893295-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-13 US disclosed
US-9893295-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-13 US disclosed
US-20160099421-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-07 US disclosed
US-20160099421-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160099421-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CYP1B1, CRY2 PDK2 1807/4885KDM4E 2333/4885MEN1 610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.