Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 10/20 | 0.73 |
| ▸ | DRD3 | P35462 | 7/20 | 0.67 |
| ▸ | DRD2 | P14416 | 5/20 | 0.67 |
| ▸ | DRD5 | P21918 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19381643 | 0.85 | DRD4 (0.67) | DRD4DRD3DRD2DRD5SMN1; SMN2 | |
| SCHEMBL17659673 | 0.76 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1MAPTHTTPARP1 | |
| SCHEMBL17659681 | 0.75 | GAA (0.41) | DRD4DRD3DRD2SMN1; SMN2KDM4E | |
| SCHEMBL29236372 | 0.75 | GAA (0.41) | DRD4DRD3DRD2SMN1; SMN2KDM4E | |
| SCHEMBL17659005 | 0.73 | DRD4 (0.57) | DRD4DRD3DRD2ALDH1A1HSD17B10 | |
| SCHEMBL17659683 | 0.72 | MAPK1 (0.52) | DRD4DRD3DRD2KDM4EMAPT | |
| SCHEMBL17659123 | 0.71 | DRD2 (0.51) | DRD4DRD3DRD2DRD5KDM4E | |
| SCHEMBL7654044 | 0.71 | HTT (0.68) | DRD4DRD3DRD2DRD5SMN1; SMN2 | |
| SCHEMBL7050984 | 0.70 | HTT (0.72) | DRD4DRD3DRD2DRD5SMN1; SMN2 | |
| SCHEMBL10679512 | 0.70 | KDM4E (0.63) | DRD4DRD3DRD2DRD5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016051799-A1 | 2-AMINOHYDROQUINONE DERIVATIVE AND TAU AGGREGATION INHIBITOR | 学校法人同志社 | 2016-04-07 | — | — | WO | disclosed |