Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17659131 | 0.76 | DRD4 (0.73) | ALDH1A1HTTSMN1; SMN2MAPTPARP1 | |
| SCHEMBL29236372 | 0.75 | GAA (0.41) | ALDH1A1HTTSMN1; SMN2MAPTCYP2C9 | |
| SCHEMBL17659681 | 0.75 | GAA (0.41) | ALDH1A1HTTSMN1; SMN2MAPTCYP2C9 | |
| Hydrochloric Acid SCHEMBL11456257 | 0.74 | DRD2 (0.50) | CYP2D6CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL17659005 | 0.73 | DRD4 (0.57) | ALDH1A1 | |
| SCHEMBL17659683 | 0.72 | MAPK1 (0.52) | MAPT | |
| SCHEMBL7171966 | 0.72 | GFER (0.59) | ALDH1A1HTTSMN1; SMN2MAPTTSHR | |
| SCHEMBL31670698 | 0.70 | SIGMAR1 (0.55) | ALDH1A1HTTSMN1; SMN2MAPTCYP2D6 | |
| SCHEMBL8045561 | 0.70 | SIGMAR1 (0.55) | ALDH1A1HTTSMN1; SMN2MAPTCYP2D6 | |
| SCHEMBL17659010 | 0.70 | GAA (0.45) | ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016051799-A1 | 2-AMINOHYDROQUINONE DERIVATIVE AND TAU AGGREGATION INHIBITOR | 学校法人同志社 | 2016-04-07 | — | — | WO | disclosed |