Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17659018 | 0.99 | HTR1A (0.52) | HTR1ASLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL17659748 | 0.94 | SLC6A2 (0.56) | HTR1ASLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL8319330 | 0.90 | NPC1 (0.52) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL17659698 | 0.89 | HTR1A (0.51) | HTR1ASLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL17659126 | 0.87 | HRH3 (0.59) | HTR1ASLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL17659140 | 0.87 | CCR5 (0.62) | HTR1ASLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL17658996 | 0.87 | HTR1A (0.72) | HTR1ASLC6A2SLC6A4SLC6A3HRH3 | |
| SCHEMBL19381142 | 0.85 | MEN1 (0.54) | HTR1ASLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL19381655 | 0.84 | MEN1 (0.53) | HTR1ASLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL19381657 | 0.84 | MEN1 (0.53) | HTR1ASLC6A2SLC6A4SLC6A3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016051799-A1 | 2-AMINOHYDROQUINONE DERIVATIVE AND TAU AGGREGATION INHIBITOR | 学校法人同志社 | 2016-04-07 | — | — | WO | disclosed |