Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.72 |
| ▸ | HTR6 | P50406 | 4/20 | 0.61 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17659748 | 0.90 | SLC6A2 (0.56) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL17659705 | 0.87 | HTR1A (0.54) | HTR1ASLC6A2SLC6A4SLC6A3HRH3 | |
| SCHEMBL17659018 | 0.86 | HTR1A (0.52) | HTR1ASLC6A2SLC6A4SLC6A3EGFR | |
| SCHEMBL8251095 | 0.85 | HTR1A (0.59) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL17659698 | 0.85 | HTR1A (0.51) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL4673484 | 0.84 | HTR1A (1.00) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL17659126 | 0.84 | HRH3 (0.59) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL17659140 | 0.84 | CCR5 (0.62) | HTR1ASLC6A2SLC6A4SLC6A3PRMT5 | |
| SCHEMBL19381516 | 0.83 | HTR1A (0.67) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL8828488 | 0.83 | HTR1A (0.64) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016051799-A1 | 2-AMINOHYDROQUINONE DERIVATIVE AND TAU AGGREGATION INHIBITOR | 学校法人同志社 | 2016-04-07 | — | — | WO | disclosed |