Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17664563 | 0.85 | BCL2A1 (0.46) | BCL2A1HTR1AKDM4EALDH1A1DRD2 | |
| SCHEMBL14409702 | 0.78 | GFER (0.53) | BCL2A1HTR1AKDM4EALDH1A1DRD2 | |
| SCHEMBL22266161 | 0.78 | KCNH2 (0.62) | HTR1ADRD2DRD4CHRM2ADRA2A | |
| SCHEMBL12606898 | 0.76 | RAD52 (0.57) | KDM4EADRA2AADRA2BADRA2CSMN1; SMN2 | |
| SCHEMBL1663685 | 0.75 | MAPT (0.53) | KDM4EALDH1A1USP2SMN1; SMN2NAMPT | |
| SCHEMBL9354477 | 0.75 | ALDH1A1 (0.53) | BCL2A1HTR1AKDM4EALDH1A1DRD2 | |
| SCHEMBL12965934 | 0.74 | ALDH1A1 (0.53) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL9336021 | 0.74 | NSD2 (0.48) | BCL2A1HTR1AKDM4EALDH1A1DRD2 | |
| SCHEMBL27937113 | 0.74 | HTR1A (0.48) | BCL2A1HTR1AKDM4EALDH1A1ADRA2A | |
| SCHEMBL24590408 | 0.72 | MAPT (0.59) | KDM4EALDH1A1USP2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9321766-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-20160096832-A1 | KINASE INHIBITORS | ALLERGAN, INC. | 2016-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096832-A1 | KINASE INHIBITORS | ABL1, LCK, ERBB2 | BCL2A1 1240/4885HTR1A 3849/4885KDM4E 1393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.