SCHEMBL1766140

SCHEMBL1766140

N[C@H]1CCC[C@@H]1N(Cc1ccccc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.49
AGER Q15109 3/20 0.47
MTNR1A P48039 1/20 0.47
SLC18A3 Q16572 1/20 0.44
OPRM1 P35372 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 4/20 0.41
HPGD P15428 2/20 0.41
GLA P06280 1/20 0.41
MAOA P21397 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM3 P20309 1/20 0.41
CCR5 P51681 1/20 0.41
KCNH2 Q12809 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
USP2 O75604 1/20 0.40
MC4R P32245 1/20 0.39
MC5R P33032 1/20 0.39
MC3R P41968 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1766139 1.00 CTSD (0.49) CTSDAGERMTNR1ASLC18A3OPRM1
SCHEMBL2521503 0.97 CTSD (0.49) CTSDAGERMTNR1ASLC18A3OPRM1
SCHEMBL2521501 0.97 CTSD (0.49) CTSDAGERMTNR1ASLC18A3OPRM1
SCHEMBL2495894 0.83 SLC18A3 (0.60) CTSDAGERMTNR1ASLC18A3OPRM1
SCHEMBL6604042 0.81 CTSD (0.52) CTSDAGERMTNR1AMEN1KMT2A
SCHEMBL2733318 0.78 CTSD (0.64) CTSDAGERMTNR1AOPRM1MEN1
SCHEMBL18580124 0.78 SLC18A3 (0.62) SLC18A3OPRM1ALDH1A1MAOA
SCHEMBL18580122 0.78 SLC18A3 (0.62) SLC18A3OPRM1ALDH1A1MAOA
SCHEMBL18580121 0.78 SLC18A3 (0.62) SLC18A3OPRM1ALDH1A1MAOA
SCHEMBL16689926 0.77 MC4R (0.56) CTSDAGERMTNR1AMC4RMC5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2319825-A1 ENZYMATIC SYNTHESIS OF ENANTIOMERICALLY ENRICHED DERIVATIVES OF CIS- AND TRANS-CYCLOPENTANE-1,2-DIAMINES EntreChem, S.L. (ES) 2011-05-11 EP disclosed