Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | AGER | Q15109 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733318 | 0.87 | CTSD (0.64) | CTSDSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL5399572 | 0.86 | HSD11B1 (0.43) | CTSDSLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL2776534 | 0.85 | CTSD (0.55) | CTSDSLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL2776529 | 0.85 | CTSD (0.55) | CTSDSLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL15407540 | 0.83 | CTSD (0.52) | CTSDSLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL1976152 | 0.83 | CTSD (0.52) | CTSDSLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL1976153 | 0.83 | CTSD (0.52) | CTSDSLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL1976155 | 0.83 | CTSD (0.52) | CTSDSLC6A2SLC6A4KCNH2SLC6A3 | |
| Hydrochloric Acid SCHEMBL3357777 | 0.82 | CTSD (0.51) | CTSDSLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL2521501 | 0.81 | CTSD (0.49) | CTSDMEN1KMT2AAGERMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265891-B1 | NOVEL LIPOIC ACID HETEROCYCLIC OR BENZENE DERIVATIVES, PREPARATION AND USE THEREOF AS MEDICINES | CONSEILS DE RECH SET D APPLIC (FR) | 2004-12-29 | — | — | EP | disclosed |
| EP-1265891-A2 | NOVEL LIPOIC ACID HETEROCYCLIC OR BENZENE DERIVATIVES, PREPARATION AND USE THEREOF AS MEDICINES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001068643-A2 | NOVEL LIPOIC ACID HETEROCYCLIC OR BENZENE DERIVATIVES, PREPARATION AND USE THEREOF AS MEDICINES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-09-20 | — | — | WO | disclosed |