Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.60 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | AGER | Q15109 | 3/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23144528 | 0.87 | SLC18A3 (0.54) | SLC18A3CTSDAGERMTNR1AKCNA5 | |
| SCHEMBL1755585 | 0.86 | SLC18A3 (0.64) | SLC18A3CTSDAGERMTNR1AKCNA5 | |
| SCHEMBL17314168 | 0.84 | SLC18A3 (0.57) | SLC18A3CTSDAGERMTNR1AKCNA5 | |
| SCHEMBL17314169 | 0.84 | SLC18A3 (0.57) | SLC18A3CTSDAGERMTNR1AKCNA5 | |
| SCHEMBL17314167 | 0.84 | SLC18A3 (0.57) | SLC18A3CTSDAGERMTNR1AKCNA5 | |
| SCHEMBL1766140 | 0.83 | CTSD (0.49) | SLC18A3CTSDAGERMTNR1AMEN1 | |
| SCHEMBL1766139 | 0.83 | CTSD (0.49) | SLC18A3CTSDAGERMTNR1AMEN1 | |
| SCHEMBL19047844 | 0.82 | AGER (0.54) | SLC18A3AGERMTNR1AKCNA5MEN1 | |
| SCHEMBL3341171 | 0.82 | SLC18A3 (0.55) | SLC18A3CTSDAGERMTNR1AKCNA5 | |
| SCHEMBL12685154 | 0.81 | SLC18A3 (0.66) | SLC18A3AGERMTNR1AKCNA5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030489-B2 | Ornithine derivative | ASTELLAS PHARMA INC. (JP) | 2011-10-04 | — | — | US | disclosed |