Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1568290 | 0.79 | GPR3 (0.46) | GPR3HTR2APOLBACHECHRM2 | |
| SCHEMBL6421466 | 0.78 | GPR3 (0.44) | GPR3HTR2APOLBACHECHRM2 | |
| SCHEMBL6902476 | 0.77 | GPR3 (0.44) | GPR3HTR2APOLBACHECHRM2 | |
| SCHEMBL29711937 | 0.74 | GPR3 (0.41) | GPR3HTR2APOLBKMT2AMEN1 | |
| SCHEMBL1766128 | 0.74 | GPR3 (0.41) | GPR3HTR2APOLBACHECHRM2 | |
| SCHEMBL29893282 | 0.74 | GPR3 (0.41) | GPR3HTR2APOLBACHECHRM2 | |
| SCHEMBL224931 | 0.74 | GPR3 (0.41) | GPR3HTR2APOLBKMT2AMEN1 | |
| SCHEMBL7421342 | 0.74 | GPR3 (0.41) | GPR3HTR2APOLBKMT2AMEN1 | |
| SCHEMBL29196425 | 0.74 | GPR3 (0.41) | GPR3HTR2APOLBACHECHRM2 | |
| SCHEMBL19973035 | 0.74 | GPR3 (0.41) | GPR3HTR2APOLBACHECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989481-B2 | Indane derivatives as modulators of ion channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-08-02 | — | — | US | claimed |
| EP-2319825-A1 | ENZYMATIC SYNTHESIS OF ENANTIOMERICALLY ENRICHED DERIVATIVES OF CIS- AND TRANS-CYCLOPENTANE-1,2-DIAMINES | EntreChem, S.L. (ES) | 2011-05-11 | — | — | EP | claimed |
| US-7605174-B2 | Indane derivatives as modulators of ion channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-10-20 | — | — | US | claimed |
| EP-1888547-A1 | INDANE DERIVATIVES AS MODULATORS OF ION CHANNELS | Vertex Pharmaceuticals, Inc. (US) | 2008-02-20 | — | — | EP | claimed |
| US-20070117801-A1 | Indane derivatives as modulator of ion channels | VERTEX PHARMACEUTICALS INCORPORATED | 2007-05-24 | — | — | US | claimed |
| WO-2006133459-A1 | INDANE DERIVATIVES AS MODULATORS OF ION CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2006-12-14 | — | — | WO | claimed |
| WO-1993012091-A1 | D- AND L-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-1-CARBOXYLIC ACIDS AND THEIR DERIVATIVES CONTAINING URETHANE-TYPE N-PROTECTING GROUPS AS WELL AS A PROCESS FOR PREPARING THEM AND THE CORRESPONDING RACEMATES | Gyógyszerkutató Intézet Kft. (HU) | 1993-06-24 | — | — | WO | claimed |
| US-11846884-B2 | Chemically amplified resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-12-19 | — | — | US | disclosed |
| US-11835859-B2 | Resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-12-05 | — | — | US | disclosed |
| CN-116165846-A | Positive resist material and pattern forming method | 信越化学工业株式会社 | 2023-05-26 | — | — | CN | disclosed |
| US-20230161252-A1 | POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-05-25 | — | — | US | disclosed |
| US-20230152692-A1 | CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-05-18 | — | — | US | disclosed |
| US-11644753-B2 | Resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-05-09 | — | — | US | disclosed |
| US-20030091931-A1 | Benzbisazole compound and optical recording medium containing the compound | MITSUI CHEMICALS, INC. (JP) | 2003-05-15 | — | — | US | disclosed |
| US-6509463-B1 | Isocyanoalkylcarbonic acid derivatives, the reaction thereof in isocyanide multicomponent reactions to form sec-amido-alkylcarbonic acid derivatives, and those sec-amidoalkyl-carbonic acid derivatives | UGICHEM GMBH (DE) | 2003-01-21 | — | — | US | disclosed |
| EP-1245571-A1 | BENZBISAZOLE COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING THE COMPOUND | Mitsui Chemicals, Inc. (JP) | 2002-10-02 | — | — | EP | disclosed |
| EP-1180765-A1 | Optical recording medium and porphycene compound | Mitsui Chemicals, Inc. (JP) | 2002-02-20 | — | — | EP | disclosed |
| US-6147240-A | Isocyanoalkyl carbonic acid derivatives, their conversion into secondary amidoalkyl carbonic acid derivatives by isocyanide-multicomponent reactions, as well as these secondary amidoalkyl carbonic acid derivatives | UGICHEM GMBH (DE) | 2000-11-14 | — | — | US | disclosed |
| EP-1000016-A1 | ISOCYANOALKYL CARBONIC ACID DERIVATIVES, THEIR CONVERSION INTO SECONDARY AMIDOALKYL CARBONIC ACID DERIVATIVES BY ISOCYANIDE-MULTICOMPONENT REACTIONS, AS WELL AS THESE SECONDARY AMIDOALKYL CARBONIC ACID DERIVATIVES. | Ugichem GmbH (DE) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999005093-A1 | ISOCYANOALKYL CARBONIC ACID DERIVATIVES, THEIR CONVERSION INTO SECONDARY AMIDOALKYL CARBONIC ACID DERIVATIVES BY ISOCYANIDE-MULTICOMPONENT REACTIONS, AS WELL AS THESE SECONDARY AMIDOALKYL CARBONIC ACID DERIVATIVES. | UGICHEM GMBH (DE) | 1999-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030091931-A1 | Benzbisazole compound and optical recording medium containing the compound | DAO, CACNA1I, KCNB2 | GPR3 659/4885HTR2A 671/4885POLB 3916/4885 |
| US-11644753-B2 | Resist composition and patterning process | HNRNPU, NSUN2, HNRNPR | GPR3 2485/4885HTR2A 3805/4885POLB 154/4885 |
| US-20070117801-A1 | Indane derivatives as modulator of ion channels | KCNJ2, TRPV1, KCNJ1 | GPR3 440/4885HTR2A 379/4885POLB 4804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.