SCHEMBL224931

SCHEMBL224931

O=CC1c2ccccc2-c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.41
HTR2A P28223 1/20 0.41
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
NCOR2 Q9Y618 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
POLB P06746 1/20 0.39
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
CDC25B P30305 1/20 0.35
CYP1A2 P05177 2/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29711937 1.00 GPR3 (0.41) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL7754656 0.86 MEN1 (0.38) CA1CA2KMT2AMEN1ALDH1A1
SCHEMBL10348682 0.84 PPIA (0.39) GPR3HTR2AHDAC3HDAC4HDAC7
Hydrochloric Acid SCHEMBL11465934 0.83 MEN1 (0.36) KMT2AMEN1ALDH1A1LMNATHRB
Iodide SCHEMBL11463652 0.83 MEN1 (0.36) KMT2AMEN1ALDH1A1LMNATHRB
SCHEMBL28543582 0.82 CA1 (0.31) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL15048581 0.82 CYP1A2 (0.45) HDAC3HDAC4HDAC7HDAC8HDAC6
SCHEMBL13500229 0.82 ELANE (0.44) GPR3KMT2AMEN1CYP1A2ALDH1A1
SCHEMBL8518637 0.82 ALDH1A1 (0.44) HTR2ACA1CA2POLBKMT2A
SCHEMBL7421342 0.79 GPR3 (0.41) GPR3HTR2AHDAC3HDAC4HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 448 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118908982-A Alkyl zinc complex and preparation method and application thereof 阜阳师范大学 2024-11-08 CN claimed
CN-115521195-B Preparation method of fluorene formaldehyde compound 上海如鲲新材料股份有限公司 2024-01-26 CN claimed
CN-117269400-A Analysis method for total aldehyde content in industrial ethylene 宝来利安德巴赛尔石化有限公司 2023-12-22 CN claimed
CN-111587403-B Composition for hard mask 东友精细化工有限公司 2023-09-19 CN claimed
CN-116669453-A Light emitting device, electronic device comprising the same, and mixture 三星电子株式会社 2023-08-29 CN claimed
CN-115521195-A Preparation method of fluorene formaldehyde compound 上海如鲲新材料股份有限公司 2022-12-27 CN claimed
CN-112724003-B Preparation method of 9-fluorenylformaldehyde 常州吉恩药业有限公司 2022-12-27 CN claimed
CN-114685538-A Boron-nitrogen compound and organic light-emitting device prepared from same 江苏三月科技股份有限公司 2022-07-01 CN claimed
CN-114447241-A Heterocyclic compound, light-emitting device, and electronic device 三星显示有限公司 2022-05-06 CN claimed
CN-114300627-A Heterocyclic compound, light-emitting element including the same, and electronic device 三星显示有限公司 2022-04-08 CN claimed
CN-1884242-A Method for preparing 9-fluorenylmethanol SHANGHAI BAOSTEEL CHEMICAL CO (CN) 2006-12-27 CN claimed
US-6872809-B2 Nucleoside derivatives JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2005-03-29 US claimed
US-20030208050-A1 Nucleoside derivatives JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-11-06 US claimed
EP-1295891-A1 NUCLEOSIDE DERIVATIVES Japan Science and Technology Corporation (JP) 2003-03-26 EP claimed
US-5721210-A OLIGOPEPTIDES AS ANTIINFLAMMATORY AGENTS OR INTEGRIN RECEPTOR ANTAGONISTS TANABE SEIYAKU CO., LTD. (JP) 1998-02-24 US claimed
EP-0538399-A4 1994-05-04 EP claimed
EP-0538399-A1 CYCLIC CELL ADHESION MODULATION COMPOUNDS TANABE SEIYAKU CO., LTD. (JP) 1993-04-28 EP claimed
WO-1992000995-A1 CYCLIC CELL ADHESION MODULATION COMPOUNDS TANABE SEIYAKU CO. LTD. (JP) 1992-01-23 WO claimed
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030208050-A1 Nucleoside derivatives RIMKLA, MTHFD1, AADAT GPR3 3300/4885HTR2A 1493/4885HDAC3 3991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.