Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192134 | 0.87 | GABBR2 (0.42) | GABBR2GABBR1ALDH1A1 | |
| SCHEMBL9323831 | 0.84 | GABBR2 (0.40) | GABBR2GABBR1ALDH1A1 | |
| SCHEMBL9323883 | 0.84 | GABBR2 (0.40) | GABBR2GABBR1ALDH1A1 | |
| SCHEMBL1875383 | 0.79 | ANPEP (0.41) | GABBR2GABBR1ALDH1A1 | |
| SCHEMBL30410005 | 0.77 | ALDH1A1 (0.45) | GABBR2GABBR1ALDH1A1 | |
| SCHEMBL13171280 | 0.77 | GABBR2 (0.36) | GABBR2GABBR1ALDH1A1 | |
| SCHEMBL20877861 | 0.77 | ALDH1A1 (0.45) | GABBR2GABBR1ALDH1A1 | |
| SCHEMBL10821968 | 0.74 | — | — | |
| SCHEMBL12850147 | 0.74 | — | — | |
| SCHEMBL13602601 | 0.74 | ALDH1A1 (0.33) | GABBR2GABBR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160096827-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2016-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096827-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | TBKBP1, TNKS1BP1, TNKS | GABBR2 3423/4885GABBR1 3538/4885ALDH1A1 4260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.