Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711165 | 0.86 | RAB9A (0.49) | MEN1KMT2ALMNASMN1; SMN2RAB9A | |
| SCHEMBL1711629 | 0.80 | PSEN1 (0.39) | SMN1; SMN2RAB9AL3MBTL1ALOX15ALDH1A1 | |
| SCHEMBL17665662 | 0.75 | MEN1 (0.43) | MEN1KMT2ALMNASMN1; SMN2CNR1 | |
| SCHEMBL27295005 | 0.69 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2CNR1GAA | |
| SCHEMBL3711683 | 0.66 | RAB9A (0.54) | KMT2ALMNASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL31252010 | 0.66 | NOS1 (0.36) | — | |
| SCHEMBL20491004 | 0.66 | CYP3A4 (0.45) | SMN1; SMN2RAB9AGAAL3MBTL1TSHR | |
| SCHEMBL1025097 | 0.64 | RAB9A (0.52) | SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL17665660 | 0.64 | MEN1 (0.43) | MEN1KMT2ALMNASMN1; SMN2CNR1 | |
| SCHEMBL17665731 | 0.64 | MEN1 (0.46) | MEN1KMT2ALMNASMN1; SMN2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016051193-A1 | COMPOUNDS USEFUL AS CSF1 MODULATORS | REDX PHARMA PLC (GB) | 2016-04-07 | — | — | WO | disclosed |