Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17665491 | 0.75 | MEN1 (0.42) | MEN1KMT2AL3MBTL1GAALMNA | |
| SCHEMBL22143470 | 0.72 | ALDH1A1 (0.46) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21539717 | 0.67 | LMNA (0.45) | MEN1KMT2AL3MBTL1GAALMNA | |
| SCHEMBL17665722 | 0.66 | MEN1 (0.47) | MEN1KMT2AL3MBTL1GAALMNA | |
| SCHEMBL19236918 | 0.66 | MEN1 (0.46) | MEN1KMT2AL3MBTL1GAALMNA | |
| SCHEMBL17665731 | 0.66 | MEN1 (0.46) | MEN1KMT2AL3MBTL1GAALMNA | |
| SCHEMBL20710061 | 0.65 | DGAT1 (0.36) | ALDH1A1 | |
| SCHEMBL15492955 | 0.64 | ALDH1A1 (0.38) | MEN1KMT2AL3MBTL1GAALMNA | |
| SCHEMBL20710059 | 0.64 | RPS6KB1 (0.35) | TSHRALDH1A1CYP2C19 | |
| SCHEMBL17665660 | 0.63 | MEN1 (0.43) | MEN1KMT2AL3MBTL1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016051193-A1 | COMPOUNDS USEFUL AS CSF1 MODULATORS | REDX PHARMA PLC (GB) | 2016-04-07 | — | — | WO | disclosed |