SCHEMBL17666352

SCHEMBL17666352

C=CC[C@](C)(O)C(=O)OC

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
CYP2C19 P33261 1/20 0.37
MAPT P10636 3/20 0.37
POLB P06746 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
DGAT1 O75907 1/20 0.35
MMP1 P03956 1/20 0.33
MMP9 P14780 1/20 0.33
MMP13 P45452 1/20 0.33
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL629663 1.00 ALDH1A1 (0.38) ALDH1A1LMNACYP2C19MAPTPOLB
SCHEMBL27412775 0.82 MAPT (0.41) ALDH1A1LMNACYP2C19MAPTPOLB
SCHEMBL3181055 0.80 CYP2C19 (0.38) ALDH1A1LMNACYP2C19MAPTPOLB
SCHEMBL631049 0.80 CYP2C19 (0.38) ALDH1A1LMNACYP2C19MAPTPOLB
SCHEMBL28157325 0.80 CYP2C19 (0.38) ALDH1A1LMNACYP2C19MAPTPOLB
SCHEMBL26699486 0.80 CYP2C19 (0.38) ALDH1A1LMNACYP2C19MAPTPOLB
Ammonia Solution, Strong SCHEMBL16982684 0.80 MAPT (0.40) ALDH1A1LMNACYP2C19MAPTPOLB
SCHEMBL2053110 0.80 CYP2C19 (0.38) ALDH1A1LMNACYP2C19MAPTPOLB
SCHEMBL2710202 0.79 PKM (0.40) ALDH1A1LMNAMAPT
Ammonia Solution, Strong SCHEMBL16895224 0.78 CYP2C19 (0.37) ALDH1A1LMNACYP2C19MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160096810-A1 ENANTIOSELECTIVE SYNTHESIS OF DIALKYLATED N,O-HETEROCYCLES BY PALLADIUM-CATALYZED ALLYLIC ALKYLATION CALIFORNIA INSTITUTE OF TECHNOLOGY 2016-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160096810-A1 ENANTIOSELECTIVE SYNTHESIS OF DIALKYLATED N,O-HETEROCYCLES BY PALLADIUM-CATALYZED ALLYLIC ALKYLATION ODC1, OSTC, AOC1 ALDH1A1 561/4885LMNA 2884/4885CYP2C19 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.