SCHEMBL17215746

SCHEMBL17215746

Cc1ccc2c(n1)oc1c(-c3nccc4ccccc34)cccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.40
KDM4E B2RXH2 5/20 0.39
NPC1 O15118 5/20 0.39
MAPT P10636 5/20 0.39
RAB9A P51151 4/20 0.39
ALDH1A1 P00352 4/20 0.39
HPGD P15428 3/20 0.39
HSD17B10 Q99714 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
MAPK1 P28482 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CASP1 P29466 1/20 0.39
CYP2C19 P33261 1/20 0.39
CASP7 P55210 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
GPR55 Q9Y2T6 1/20 0.39
GLA P06280 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30051501 0.85 KDM4E (0.43) CYP2A6KDM4ENPC1MAPTRAB9A
SCHEMBL17666809 0.85 KDM4E (0.43) CYP2A6KDM4ENPC1MAPTRAB9A
SCHEMBL24087566 0.85 SCN9A (0.32) SCN9A
SCHEMBL25822929 0.84 ABCB1 (0.36) ALDH1A1HPGDSCN9A
SCHEMBL25822951 0.82 SCN9A (0.35) SCN9A
SCHEMBL22170799 0.81 CYP2A6 (0.44) CYP2A6KDM4ENPC1MAPTRAB9A
SCHEMBL22096474 0.81 CYP1A2 (0.44) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL15672843 0.80 SMN1; SMN2 (0.41) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL16441295 0.80 TGFBR1 (0.39) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL26061121 0.79 SCN9A (0.31) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11919916-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-03-05 US disclosed
US-20220348600-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-11-03 US disclosed
US-11427607-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-08-30 US disclosed
US-10457699-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-10-29 US disclosed
US-10457699-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-10-29 US disclosed
EP-2940098-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2018-01-17 EP disclosed
EP-2940098-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2018-01-17 EP disclosed
US-20150315222-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-11-05 US disclosed
US-20150315222-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-11-05 US disclosed
US-20150315222-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-11-05 US disclosed
EP-2940098-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2015-11-04 EP disclosed
EP-2940098-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2015-11-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150315222-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, SSB, RPS4X CYP2A6 3805/4885KDM4E 759/4885NPC1 4462/4885
US-10457699-B2 Organic electroluminescent materials and devices MLX, SSB, RPS4X CYP2A6 3805/4885KDM4E 759/4885NPC1 4462/4885
US-20220348600-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, SSB, LOXL4 CYP2A6 3533/4885KDM4E 1666/4885NPC1 3062/4885
US-11427607-B2 Organic electroluminescent materials and devices MLX, SSB, LOXL4 CYP2A6 3533/4885KDM4E 1666/4885NPC1 3062/4885
US-11919916-B2 Organic electroluminescent materials and devices MLX, SSB, LBR CYP2A6 3304/4885KDM4E 1781/4885NPC1 2958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.