SCHEMBL24796189

SCHEMBL24796189

c1ccc2c(-c3cccc4c3oc3ncccc34)ncnc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.45
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 2/20 0.38
PIK3CA P42336 2/20 0.38
PI4KA P42356 1/20 0.37
PI4K2B Q8TCG2 1/20 0.37
PI4K2A Q9BTU6 1/20 0.37
PI4KB Q9UBF8 1/20 0.37
PDE4A P27815 1/20 0.37
PDE4B Q07343 1/20 0.37
PDE4C Q08493 1/20 0.37
PDE4D Q08499 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
GRM4 Q14833 1/20 0.35
SGMS2 Q8NHU3 4/20 0.35
ATR Q13535 1/20 0.35
ADK P55263 1/20 0.35
MAPT P10636 3/20 0.34
EGFR P00533 1/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24596447 0.82 ADK (0.47) ADORA2AKDM4EALDH1A1PI4KAPI4K2B
SCHEMBL17666809 0.78 KDM4E (0.43) KDM4EALDH1A1PIK3CASMN1; SMN2MAPT
SCHEMBL30051501 0.78 KDM4E (0.43) KDM4EALDH1A1PIK3CASMN1; SMN2MAPT
SCHEMBL23996441 0.78 KDM4E (0.44) KDM4EALDH1A1PIK3CAPI4KBMAPT
SCHEMBL15695118 0.75 ALDH1A1 (0.44) KDM4EALDH1A1PIK3CASMN1; SMN2MAPT
SCHEMBL25461671 0.75 ADORA2A (0.43) ADORA2AKDM4EALDH1A1PI4KAPI4K2B
SCHEMBL29381921 0.75 LMNA (0.49) ADORA2AKDM4EALDH1A1PIK3CAPI4KA
SCHEMBL15673006 0.74 KDM4E (0.43) KDM4EALDH1A1PIK3CASMN1; SMN2MAPT
SCHEMBL29906205 0.74 KDM4E (0.43) KDM4EALDH1A1PIK3CASMN1; SMN2MAPT
SCHEMBL18252207 0.74 KDM4E (0.42) KDM4EALDH1A1PIK3CAPI4KBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220402877-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402877-A1 ELECTROLUMINESCENT DEVICE MCOLN2, MCOLN1, LDHB ADORA2A 4188/4885KDM4E 1211/4885ALDH1A1 851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.