Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.36 |
| ▸ | GBA1 | P04062 | 3/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PRKDC | P78527 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17667301 | 1.00 | HRH4 (0.36) | HRH4GBA1CTSSMEN1KMT2A | |
| SCHEMBL17667367 | 0.98 | HRH4 (0.36) | HRH4GBA1CTSSMEN1KMT2A | |
| SCHEMBL17667365 | 0.98 | HRH4 (0.36) | HRH4GBA1CTSSMEN1KMT2A | |
| SCHEMBL17627935 | 0.86 | PRKDC (0.39) | HRH4GBA1MEN1KMT2APRKDC | |
| SCHEMBL17667275 | 0.86 | HRH4 (0.35) | HRH4GBA1CTSSMEN1KMT2A | |
| SCHEMBL17628075 | 0.84 | PRKDC (0.39) | HRH4GBA1CTSSMEN1KMT2A | |
| SCHEMBL17667289 | 0.84 | HRH4 (0.35) | HRH4GBA1CTSSMEN1KMT2A | |
| SCHEMBL17667274 | 0.81 | SPR (0.43) | HRH4GBA1PRKDCTP53GLA | |
| SCHEMBL17667288 | 0.79 | SPR (0.45) | HRH4GBA1CTSSPRKDCLMNA | |
| SCHEMBL17628349 | 0.78 | HRH4 (0.41) | HRH4CTSSMEN1KMT2APRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006439-A1 | BICYCLIC DERIVATIVE CONTAINING PYRIMIDINE RING, AND PREPARATION METHOD THEREFOR | Yuhan Corporation (KR) | 2016-04-13 | — | — | EP | disclosed |