SCHEMBL17674207

SCHEMBL17674207

CCOC(=O)CC(CC)[N+](=O)[O-]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.41
MGAM O43451 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
MAPT P10636 3/20 0.41
LMNA P02545 3/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 8/20 0.39
TRPA1 O75762 1/20 0.39
CYP3A4 P08684 2/20 0.37
ALOX15 P16050 2/20 0.37
TSHR P16473 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
HSD17B10 Q99714 2/20 0.36
CHRM1 P11229 1/20 0.36
ADORA1 P30542 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
MITF O75030 1/20 0.35
CYP1A2 P05177 1/20 0.34
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2013748 0.87 MAPT (0.40) GAAMGAMSIMGAM2MAPT
SCHEMBL10418827 0.85 L3MBTL1 (0.44) GAAMGAMSIMGAM2MAPT
SCHEMBL13597713 0.85 MAPT (0.40) GAAMGAMSIMGAM2MAPT
SCHEMBL11513193 0.83 L3MBTL1 (0.45) GAAMGAMSIMGAM2MAPT
SCHEMBL17674174 0.82 TSHR (0.36) GAAMGAMSIMGAM2MAPT
SCHEMBL10748030 0.82 NAAA (0.42) MAPTALDH1A1TSHRTDP1L3MBTL1
SCHEMBL17674109 0.81 CPA1 (0.40) GAAMGAMSIMGAM2MAPT
SCHEMBL17673860 0.81 MAPT (0.37) GAAMGAMSIMGAM2MAPT
SCHEMBL10833248 0.79 ALDH1A1 (0.33) ALDH1A1
SCHEMBL25295269 0.78 L3MBTL1 (0.47) GAAMGAMSIMGAM2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364300-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-07-30 US claimed
US-20170247478-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2017-08-31 US claimed
EP-3204429-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2017-08-16 EP claimed
WO-2016057388-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-04-14 WO claimed
CN-107567464-B Process for producing polydienes and polydiene copolymers having reduced cold flow properties 株式会社普利司通 2020-04-14 CN disclosed
US-10364300-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-07-30 US disclosed
EP-3204429-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2018-09-05 EP disclosed
US-20170247478-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2017-08-31 US disclosed
EP-3204429-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2017-08-16 EP disclosed
WO-2016057388-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-04-14 WO disclosed