Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.45 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | S100A4 | P26447 | 3/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6396044 | 0.94 | ALDH1A1 (0.57) | ALDH1A1TDP1HPRT1LMNAABCC8 | |
| SCHEMBL29236231 | 0.88 | ALDH1A1 (0.59) | ALDH1A1TDP1HPRT1LMNAABCC8 | |
| SCHEMBL12661145 | 0.88 | ALDH1A1 (0.55) | ALDH1A1TDP1HPRT1LMNAABCC8 | |
| SCHEMBL1392515 | 0.88 | TDP1 (0.71) | ALDH1A1TDP1HPRT1MEN1KMT2A | |
| SCHEMBL29878887 | 0.86 | GPR35 (0.56) | ALDH1A1TDP1HPRT1ABCC8KCNJ11 | |
| SCHEMBL4583260 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TDP1HPRT1LMNAABCC8 | |
| SCHEMBL9107313 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TDP1HPRT1LMNAABCC8 | |
| SCHEMBL2234399 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TDP1HPRT1LMNAABCC8 | |
| SCHEMBL7695298 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TDP1HPRT1LMNAABCC8 | |
| SCHEMBL5887502 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TDP1HPRT1LMNAABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016870-B | One contains meta-terphenyl structure diamine compound and synthetic method thereof and application | 中山大学 | 2017-01-04 | — | — | CN | claimed |
| CN-104016870-A | Diamine compound with meta-terphenyl structure as well as synthetic method and application thereof | UNIV SUN YAT SEN | 2014-09-03 | — | — | CN | claimed |
| US-20210002270-A1 | TRICYCLIC SPACER SYSTEMS FOR NONLINEAR OPTICAL DEVICES | LIGHTWAVE LOGIC, INC. | 2021-01-07 | — | — | US | disclosed |
| CN-109195963-A | 6-hydroxy-4-oxo-1, 4-dihydropyrimidine-5-carboxamides as APJ agonists | 百时美施贵宝公司 | 2019-01-11 | — | — | CN | disclosed |
| US-20180044333-A1 | Tricyclic Spacer Systems for Nonlinear Optical Devices | GOETZ JENNIFER (US) | 2018-02-15 | — | — | US | disclosed |
| US-20170204091-A1 | TRICYCLIC SPACER SYSTEMS FOR NONLINEAR DEVICES | LIGHTWAVE LOGIC INC (US) | 2017-07-20 | — | — | US | disclosed |
| US-20140121376-A1 | TRICYCLIC SPACER SYSTEMS FOR NONLINEAR OPTICAL DEVICES | LIGHTWAVE LOGIC, INC. (US) | 2014-05-01 | — | — | US | disclosed |
| US-8298326-B2 | Tricyclic spacer systems for nonlinear optical devices | GOETZ SR FREDERICK J (US) | 2012-10-30 | — | — | US | disclosed |
| US-20110112295-A1 | TRICYCLIC SPACER SYSTEMS FOR NONLINEAR OPTICAL DEVICES | Lightwave Logic Inc. (US) | 2011-05-12 | — | — | US | disclosed |
| US-20080009620-A1 | Tricyclic Spacer Systems For Nonlinear Optical Devices | THIRD-ORDER NANOTECHNOLOGIES, INC. (US) | 2008-01-10 | — | — | US | disclosed |
| EP-1805157-A2 | TRICYCLIC SPACER SYSTEMS FOR NONLINEAR OPTICAL DEVICES | Third-Order Nanotechnologies, Inc. (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006047772-A2 | TRICYCLIC SPACER SYSTEMS FOR NONLINEAR OPTICAL DEVICES | THIRD-ORDER NANOTECHNOLOGIES, INC. (US) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009620-A1 | Tricyclic Spacer Systems For Nonlinear Optical Devices | AQP4, CCND3, CDK14 | ALDH1A1 3822/4885TDP1 2599/4885HPRT1 3334/4885 |
| US-20140121376-A1 | TRICYCLIC SPACER SYSTEMS FOR NONLINEAR OPTICAL DEVICES | AQP4, CCND3, CDK14 | ALDH1A1 3822/4885TDP1 2599/4885HPRT1 3334/4885 |
| US-20170204091-A1 | TRICYCLIC SPACER SYSTEMS FOR NONLINEAR DEVICES | CCND3, CCNY, CCND2 | ALDH1A1 3982/4885TDP1 2297/4885HPRT1 2829/4885 |
| US-20110112295-A1 | TRICYCLIC SPACER SYSTEMS FOR NONLINEAR OPTICAL DEVICES | AQP4, CCND3, CDK14 | ALDH1A1 3822/4885TDP1 2599/4885HPRT1 3334/4885 |
| US-20210002270-A1 | TRICYCLIC SPACER SYSTEMS FOR NONLINEAR OPTICAL DEVICES | AQP4, CCND3, CDK14 | ALDH1A1 3822/4885TDP1 2599/4885HPRT1 3334/4885 |
| US-20180044333-A1 | Tricyclic Spacer Systems for Nonlinear Optical Devices | AQP4, CCND3, CDK14 | ALDH1A1 3822/4885TDP1 2599/4885HPRT1 3334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.