SCHEMBL4583260

SCHEMBL4583260

O=[N+]([O-])c1c(Cl)cccc1-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.53
TDP1 Q9NUW8 2/20 0.53
CYP2A6 P11509 1/20 0.52
HPRT1 P00492 1/20 0.46
MAPT P10636 2/20 0.42
ABCC8 Q09428 1/20 0.40
KCNJ11 Q14654 1/20 0.40
TSHR P16473 2/20 0.39
LMNA P02545 2/20 0.39
MAPK14 Q16539 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39
HPGD P15428 2/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26191609 0.93 ALDH1A1 (0.50) ALDH1A1TDP1CYP2A6HPRT1MAPT
SCHEMBL1767571 0.86 ALDH1A1 (0.63) ALDH1A1TDP1HPRT1ABCC8KCNJ11
SCHEMBL27756439 0.85 MEN1 (0.43) ALDH1A1TDP1CYP2A6MAPTTSHR
SCHEMBL13982734 0.84 GRIN2D (0.42) ALDH1A1TDP1HPRT1MAPTTSHR
SCHEMBL29394611 0.82 ALDH1A1 (0.51) ALDH1A1TDP1CYP2A6MAPTTSHR
SCHEMBL6396044 0.81 ALDH1A1 (0.57) ALDH1A1TDP1HPRT1MAPTABCC8
SCHEMBL25561353 0.81 TDP1 (0.43) ALDH1A1TDP1CYP2A6MAPTTSHR
SCHEMBL2495875 0.81 HSD17B10 (0.46) ALDH1A1TDP1HPRT1MAPTTSHR
SCHEMBL13983293 0.80 APP (0.47) ALDH1A1MAPTLMNAHPGDPKM
SCHEMBL6497467 0.80 ALDH1A1 (0.47) ALDH1A1TDP1CYP2A6HPRT1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122032423-A Catalyst for continuous production of 4' -chloro-2-aminobiphenyl, reaction system and process 厦门嘉氢科技有限公司 2026-05-15 CN claimed
CN-112358402-B Preparation method of 4' -chloro-2-nitrobiphenyl 湖南海利常德农药化工有限公司 2022-11-29 CN claimed
CN-110325513-A The method for preparing substituted biphenyl 巴斯夫欧洲公司 2019-10-11 CN claimed
CN-109563023-A The method for preparing substituted biphenyl 巴斯夫欧洲公司 2019-04-02 CN claimed
CN-109553535-A A kind of method that one kettle way prepares the chloro- 2`- nitrobiphenyl of 4- 宁波赜军医药科技有限公司 2019-04-02 CN claimed
CN-106631812-A Preparation method of 4'-chloro-2-nitro-1,1'-biphenyl serving as boscalid intermediate 浙江工业大学 2017-05-10 CN claimed
CN-105218378-A Prepare the method for substituted biphenyl BASF SE 2016-01-06 CN claimed
CN-104478797-A Preparation method of nicotinamide fungicide namely boscalid SUZHOU TOKIND CHEMICAL CO LTD 2015-04-01 CN claimed
CN-102076651-A Process for preparing substituted biphenyls BASF SE 2011-05-25 CN claimed
CN-122102915-A Preparation method of boscalid intermediate 4' -chloro-2-nitrobiphenyl 2026-05-29 CN disclosed
CN-122032423-A Catalyst for continuous production of 4' -chloro-2-aminobiphenyl, reaction system and process 厦门嘉氢科技有限公司 2026-05-15 CN disclosed
CN-116640064-B Synthesis method of 4' -chloro-2-aminobiphenyl 山东京博农化科技股份有限公司 2025-03-04 CN disclosed
CN-115974697-B Method for catalytic synthesis of 4' -chloro-2-nitrobiphenyl 南京工业大学 2024-11-05 CN disclosed
CN-117534574-A Biphenyl diamine compound and preparation method and application thereof 阜阳欣奕华材料科技有限公司 2024-02-09 CN disclosed
CN-101767018-A Loading type Pd base metal nanometer cluster catalyst, preparing method and applications thereof UNIV BEIJING 2010-07-07 CN disclosed
CN-101133016-B Method for producing substituted biphenyls BASF AG 2010-06-02 CN disclosed
EP-1935486-A1 Method for processing mixture of materials BASF SE (DE) 2008-06-25 EP disclosed
CN-101133016-A Method for producing substituted biphenyls BASF AG (DE) 2008-02-27 CN disclosed
CN-1163452-C Process for preparing nitrobiphenylene �����ɷ� 2004-08-25 CN disclosed
CN-1213359-A Process for preparing nitrobiphenylene BASF AG (DE) 1999-04-07 CN disclosed