Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 12/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13827227 | 0.91 | SLC6A9 (0.53) | SLC6A9KCNH2KMT2ALMNAMEN1 | |
| SCHEMBL13737074 | 0.87 | SLC6A9 (0.69) | SLC6A9KCNH2KMT2ALMNAMEN1 | |
| SCHEMBL13827334 | 0.86 | SLC6A9 (0.51) | SLC6A9KCNH2KMT2ALMNAMEN1 | |
| SCHEMBL13827488 | 0.84 | KDM1A (0.42) | SLC6A9KCNH2GAABCHEACHE | |
| SCHEMBL13827231 | 0.82 | SLC6A9 (0.59) | SLC6A9KCNH2KMT2ALMNAMEN1 | |
| SCHEMBL13827487 | 0.82 | SLC6A9 (0.41) | SLC6A9KCNH2GAABCHEACHE | |
| SCHEMBL13736345 | 0.81 | SLC6A9 (0.49) | SLC6A9KCNH2KMT2ALMNAMEN1 | |
| SCHEMBL13736151 | 0.81 | SLC6A9 (0.48) | SLC6A9KCNH2GAABCHEACHE | |
| SCHEMBL13827329 | 0.81 | SLC6A9 (0.67) | SLC6A9KCNH2KMT2ALMNAMEN1 | |
| SCHEMBL603332 | 0.81 | SLC6A9 (0.67) | SLC6A9KCNH2KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309200-B2 | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-04-12 | — | — | US | disclosed |