Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15727275 | 0.90 | ALDH1A1 (0.31) | ALDH1A1GAA | |
| SCHEMBL23736111 | 0.85 | SLC6A2 (0.32) | ALDH1A1GAA | |
| SCHEMBL26481205 | 0.70 | HDAC3 (0.33) | ALDH1A1GAA | |
| SCHEMBL15726434 | 0.68 | PDE4B (0.35) | ALDH1A1GAA | |
| SCHEMBL15727144 | 0.67 | PDE4B (0.34) | GAA | |
| SCHEMBL806691 | 0.66 | GAA (0.33) | GAA | |
| SCHEMBL15727268 | 0.66 | TERF2 (0.30) | ALDH1A1GAA | |
| SCHEMBL23736080 | 0.65 | HDAC3 (0.34) | GAA | |
| SCHEMBL16003016 | 0.64 | CXCR2 (0.33) | — | |
| SCHEMBL17282907 | 0.64 | GAA (0.33) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309285-B2 | Macrocyclic broad spectrum antibiotics | RQX PHARMACEUTICALS, INC. (US) | 2016-04-12 | — | — | US | disclosed |