Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16384325 | 0.80 | MAOA (0.50) | DRD2DRD1DRD3 | |
| Hydrochloric Acid SCHEMBL31195438 | 0.79 | MAOA (0.52) | DRD2DRD1DRD3MAPT | |
| SCHEMBL6369524 | 0.77 | HRH3 (0.51) | HRH3DRD2DRD1PNMTDRD3 | |
| SCHEMBL8569648 | 0.76 | DRD1 (0.50) | DRD2DRD1DRD3 | |
| SCHEMBL6298322 | 0.76 | HRH3 (0.50) | HRH3DRD2DRD1PNMTDRD3 | |
| SCHEMBL30561542 | 0.76 | HRH3 (0.50) | HRH3DRD2DRD1PNMTDRD3 | |
| SCHEMBL6370169 | 0.76 | HTR7 (0.51) | HRH3DRD2DRD1PNMTDRD3 | |
| SCHEMBL15636634 | 0.76 | CARM1 (0.58) | HRH3DRD2DRD1PNMTDRD3 | |
| SCHEMBL6369552 | 0.76 | PNMT (0.55) | HRH3DRD2DRD1PNMTDRD3 | |
| SCHEMBL13171826 | 0.76 | HRH3 (0.50) | HRH3DRD2DRD1PNMTDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673281-B1 | BORON CONTAINING POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTICS USES THEREOF | REMPEX PHARMACEUTICALS INC (US) | 2016-04-13 | — | — | EP | disclosed |