SCHEMBL1767908

SCHEMBL1767908

Nc1c(-c2ccccc2)cc2ccccc2c1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
KDM4E B2RXH2 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
HPGD P15428 3/20 0.50
MAPT P10636 2/20 0.50
MPI P34949 1/20 0.50
GPR84 Q9NQS5 2/20 0.45
RECQL P46063 1/20 0.42
CYP11B1 P15538 1/20 0.42
HSD17B10 Q99714 3/20 0.41
ACHE P22303 2/20 0.40
CASP1 P29466 2/20 0.40
GLA P06280 1/20 0.40
CHRM2 P08172 1/20 0.40
ADRA2A P08913 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
CHRM1 P11229 1/20 0.40
NQO2 P16083 1/20 0.40
MAOA P21397 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28006789 0.85 GRM2 (0.43) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL5461463 0.85 MEN1 (0.54) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL16860069 0.84 GPR84 (0.50) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL272956 0.84 MEN1 (0.47) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL30902294 0.84 MEN1 (0.47) ALDH1A1KDM4EMEN1KMT2AHPGD
Water SCHEMBL10783729 0.82 KMT2A (0.46) ALDH1A1KDM4EMEN1KMT2AHPGD
Ammonia Solution, Strong SCHEMBL29267919 0.82 MEN1 (0.46) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL31373837 0.82 ALDH1A1 (0.50) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL8723113 0.82 MEN1 (0.55) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL11788064 0.82 KMT2A (0.55) ALDH1A1KDM4EMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2552977-A1 MULTIPLE FUNCTION GRAFT POLYMER Castrol Limited (GB) 2013-02-06 EP claimed
EP-2501726-A1 MULTIFUNCTIONAL MULTIPLE GRAFT MONOMER LOW MOLECULAR WEIGHT POLYMER Castrol Limited (GB) 2012-09-26 EP claimed
WO-2011123408-A1 MULTIPLE FUNCTION GRAFT POLYMER CASTROL LIMITED (GB) 2011-10-06 WO claimed
WO-2011062914-A1 MULTIFUNCTIONAL MULTIPLE GRAFT MONOMER LOW MOLECULAR WEIGHT POLYMER CASTROL LIMITED (GB) 2011-05-26 WO claimed
CN-109643074-A Electrophtography photosensor, handle box and image forming apparatus 京瓷办公信息系统株式会社 2019-04-16 CN disclosed
CN-109074009-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 京瓷办公信息系统株式会社 2018-12-21 CN disclosed
CN-103031193-B Lubricant oil composite 雪佛龙日本有限公司 2016-10-26 CN disclosed
EP-2552977-A1 MULTIPLE FUNCTION GRAFT POLYMER Castrol Limited (GB) 2013-02-06 EP disclosed
EP-2501726-A1 MULTIFUNCTIONAL MULTIPLE GRAFT MONOMER LOW MOLECULAR WEIGHT POLYMER Castrol Limited (GB) 2012-09-26 EP disclosed
WO-2011123408-A1 MULTIPLE FUNCTION GRAFT POLYMER CASTROL LIMITED (GB) 2011-10-06 WO disclosed
WO-2011062914-A1 MULTIFUNCTIONAL MULTIPLE GRAFT MONOMER LOW MOLECULAR WEIGHT POLYMER CASTROL LIMITED (GB) 2011-05-26 WO disclosed
EP-1513794-A4 PREPARATION OF MONOMERS FOR GRAFTING TO POLYOLEFINS, AND LUBRICATING OIL COMPOSITIONS CONTAINING GRAFTED COPOLYMER CASTROL LTD (GB) 2008-09-10 EP disclosed
EP-1874837-A1 MULTIPLE-FUNCTION DISPERSANT GRAFT POLYMER CASTROL LIMITED (GB) 2008-01-09 EP disclosed
WO-2006116663-A1 MULTIPLE-FUNCTION DISPERSANT GRAFT POLYMER CASTROL LIMITED (GB) 2006-11-02 WO disclosed
EP-1513794-A2 PREPARATION OF MONOMERS FOR GRAFTING TO POLYOLEFINS, AND LUBRICATING OIL COMPOSITIONS CONTAINING GRAFTED COPOLYMER CASTROL LIMITED (GB) 2005-03-16 EP disclosed
EP-1029890-B1 Aliphatic polyester composition and stretched film obtained from said composition MITSUI CHEMICALS INC (JP) 2004-07-28 EP disclosed
WO-2003099890-A2 PREPARATION OF MONOMERS FOR GRAFTING TO POLYOLEFINS, AND LUBRICATING OIL COMPOSITIONS CONTAINING GRAFTED COPOLYMER CASTROL LIMITED (GB) 2003-12-04 WO disclosed
US-6544607-B1 To form stretched film; for producing packages MITSUI CHEMICALS, INC. (JP) 2003-04-08 US disclosed
EP-1029890-A2 Aliphatic polyester composition and stretched film obtained from said composition Mitsui Chemicals, Inc. (JP) 2000-08-23 EP disclosed