Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 5/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.44 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768167 | 0.83 | PTGER1 (0.54) | HTTADRA1ACLCN2CYP2C9TDP1 | |
| SCHEMBL3738386 | 0.77 | FFAR1 (0.54) | PTGS1CXCL8AKR1B1SUCNR1CYP2C9 | |
| SCHEMBL5429296 | 0.77 | PTGDR2 (0.56) | PTGS1CXCL8AKR1B1SUCNR1CYP2C9 | |
| SCHEMBL7540822 | 0.77 | CYP2A6 (0.41) | LMNATSHRCLCN2 | |
| SCHEMBL8645744 | 0.77 | PTGS1 (0.55) | PTGS1AKR1B1ABCC4LMNAGAA | |
| SCHEMBL4900831 | 0.77 | CXCL8 (0.50) | PTGS1CXCL8AKR1B1AKR1B10UGT1A9 | |
| SCHEMBL27905024 | 0.75 | PTGS1 (0.49) | PTGS1CXCL8AKR1B1ABCC4LMNA | |
| SCHEMBL5382426 | 0.75 | PTGS1 (0.61) | PTGS1AKR1B1ABCC4LMNAGAA | |
| SCHEMBL538512 | 0.75 | KMT2A (0.60) | PTGS1AKR1B1ABCC4LMNAGAA | |
| Hydrochloric Acid SCHEMBL11408340 | 0.75 | CXCL8 (0.49) | PTGS1CXCL8AKR1B1AKR1B10UGT1A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981754-A | TREATMENT OF ANOXIA, ALZHEIMER'S DISEASE, SENILE DEMENTIA, SUBCORTICAL DEMENTIA SUCH AS HUNTINGTON'S CHOREA AND PARKINSON'S DISEASE, DEMENTIA CAUSED BY AIDS, NEUROPATHY | SANOFI (FR) | 1999-11-09 | — | — | US | disclosed |