Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792877 | 0.81 | ALDH1A1 (0.58) | PTGS2PPARGPPARAPGRADORA3 | |
| SCHEMBL6792870 | 0.81 | ALDH1A1 (0.58) | PTGS2PPARGPPARAPGRADORA3 | |
| E1501 SCHEMBL28758534 | 0.81 | ALDH1A1 (0.61) | ELANEDHODHPTGS1SLC6A2ALDH1A1 | |
| SCHEMBL28968069 | 0.80 | PSEN1 (0.52) | ELANEPTGS2PPARGPPARAPSEN1 | |
| SCHEMBL1768169 | 0.80 | PTGS2 (0.57) | PTGS2DHODHPSEN1PSEN2APH1B | |
| SCHEMBL1768327 | 0.80 | AKR1C3 (0.55) | ELANEPTGS2PPARGPPARADHODH | |
| SCHEMBL4007604 | 0.78 | ALDH1A1 (0.58) | PPARGPPARAPGRADORA3PTGS1 | |
| SCHEMBL23876179 | 0.78 | ALDH1A1 (0.47) | ELANEPTGS2PPARGPPARAPSEN1 | |
| SCHEMBL5182481 | 0.77 | LMNA (0.56) | PTGS2PPARGPPARAPGRADORA3 | |
| SCHEMBL9234482 | 0.77 | LMNA (0.56) | PTGS2PPARGPPARAPGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061271-A1 | SUBSTITUTED CARBAMOYLMETHYLAMINO ACETIC ACID DERIVATIVES AS NOVEL NEP INHIBITORS | NOVARTIS AG (CH) | 2011-05-26 | — | — | WO | disclosed |