Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366191 | 0.94 | TOP1 (0.48) | TOP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10177310 | 0.87 | ALDH1A1 (0.43) | TOP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL30832982 | 0.85 | ALDH1A1 (0.52) | TOP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5568763 | 0.83 | CA1 (0.48) | TOP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL367475 | 0.83 | MAPT (0.44) | TOP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL29559535 | 0.81 | CA1 (0.52) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL4429261 | 0.81 | CA1 (0.52) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL30832984 | 0.79 | ALDH1A1 (0.58) | TOP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18795084 | 0.78 | APP (0.46) | TOP1ALDH1A1KMT2AMAPTCA1 | |
| SCHEMBL17241679 | 0.78 | APP (0.46) | TOP1ALDH1A1KDM4ETDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061439-A1 | CATALYTIC PHOSPHINATION METHOD | UNIVERSITE DE STRASBOURG (FR) | 2011-05-26 | — | — | WO | disclosed |
| US-20090105505-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2009-04-23 | — | — | US | disclosed |
| EP-1778704-B1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2008-11-26 | — | — | EP | disclosed |
| EP-1778704-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2007-05-02 | — | — | EP | disclosed |
| EP-1761549-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006002730-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2006-01-12 | — | — | WO | disclosed |
| WO-2006002731-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2006-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105505-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | C1S, KMO, C1R | TOP1 1775/4885ALDH1A1 2688/4885MEN1 1398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.