Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768355 | 0.94 | TOP1 (0.47) | TOP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10177310 | 0.89 | ALDH1A1 (0.43) | TOP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL367475 | 0.84 | MAPT (0.44) | TOP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL29559535 | 0.83 | CA1 (0.52) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL4429261 | 0.83 | CA1 (0.52) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL30037087 | 0.83 | TOP1 (0.52) | TOP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL19770514 | 0.82 | TOP1 (0.44) | TOP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5568763 | 0.80 | CA1 (0.48) | TOP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL30832982 | 0.80 | ALDH1A1 (0.52) | TOP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL367342 | 0.79 | CA1 (0.49) | ALDH1A1MEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118702740-A | Metal compound, catalytic system and application thereof | 上海化工研究院有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-118638260-A | Functionalized polyolefin and preparation method and application thereof | 上海化工研究院有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-117986304-A | Complex, catalyst system containing complex and use of catalyst system | 东华大学 | 2024-05-07 | — | — | CN | disclosed |
| CN-115246858-A | Phosphine-oxa bidentate ligand and its coordinated transition metal complex and use | 东莞市均成高新材料有限公司 | 2022-10-28 | — | — | CN | disclosed |
| US-10322410-B2 | Ligand for catalyst or pre-catalyst and method of forming C(SP2)-N bond | DALHOUSIE UNIVERSITY (CA) | 2019-06-18 | — | — | US | disclosed |
| EP-3461556-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | AbbVie Ireland Unlimited Company (IE) | 2019-04-03 | — | — | EP | disclosed |
| EP-3461556-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | AbbVie Ireland Unlimited Company (IE) | 2019-04-03 | — | — | EP | disclosed |
| EP-2593226-B1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBVIE IRELAND UNLIMITED CO (IE) | 2018-11-14 | — | — | EP | disclosed |
| US-20180141030-A1 | LIGAND FOR CATALYST OR PRE-CATALYST AND METHOD OF FORMING C(SP2)-N BOND | DALHOUSIE UNIVERSITY (CA) | 2018-05-24 | — | — | US | disclosed |
| US-9890231-B2 | Triarylphosphine or triarylarsine compound, alpha-olefin polymerization catalyst using the compound, ternary copolymer, and production process of alpha-olefin-((meth)acrylic acid)-based copolymer | JAPAN POLYETHYLENE CORPORATION (JP) | 2018-02-13 | — | — | US | disclosed |
| EP-1964857-A1 | Polymerization of acyclic aliphatic olefins | Rohm and Haas Company (US) | 2008-09-03 | — | — | EP | disclosed |
| US-20080207854-A1 | Substantially linear copolymers and methods of making the same | ROHM AND HAAS COMPANY | 2008-08-28 | — | — | US | disclosed |
| US-20080207855-A1 | Chemical resistant polymerization complex | ROHM AND HAAS COMPANY | 2008-08-28 | — | — | US | disclosed |
| US-7339075-B2 | Ligand synthesis | ROHM AND HAAS COMPANY (US) | 2008-03-04 | — | — | US | disclosed |
| US-20070287627-A1 | Single Site Palladium Catalyst Complexes | ROHM AND HAAS COMPANY (US) | 2007-12-13 | — | — | US | disclosed |
| US-20070287847-A1 | Ligand Synthesis | ROHM AND HAAS COMPANY (US) | 2007-12-13 | — | — | US | disclosed |
| EP-1762572-A1 | Process for preparing ortho-substituted phenylphosphine ligands | Rohm and Haas Company (US) | 2007-03-14 | — | — | EP | disclosed |
| EP-1760086-A2 | Single site palladium catalyst complexes | Rohm and Haas Company (US) | 2007-03-07 | — | — | EP | disclosed |
| EP-1760097-A2 | Substantially linear copolymers of olefin and polar monomers. Methods of making the same. | Rohm and Haas Company (US) | 2007-03-07 | — | — | EP | disclosed |
| US-20070049712-A1 | Substantially Linear Polymers and Methods of Making and Using Same | ROHM AND HAAS COMPANY (US) | 2007-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141030-A1 | LIGAND FOR CATALYST OR PRE-CATALYST AND METHOD OF FORMING C(SP2)-N BOND | SP1, SOD1, AP1M1 | TOP1 3337/4885ALDH1A1 1807/4885MEN1 551/4885 |
| US-10322410-B2 | Ligand for catalyst or pre-catalyst and method of forming C(SP2)-N bond | SP1, SOD1, AP1M1 | TOP1 3337/4885ALDH1A1 1807/4885MEN1 551/4885 |
| US-20070287847-A1 | Ligand Synthesis | CHD3, CRKL, CSK | TOP1 2546/4885ALDH1A1 4544/4885MEN1 1890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.