Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | SELP | P16109 | 1/20 | 0.47 |
| ▸ | SELE | P16581 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | CASR | P41180 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176835 | 1.00 | NPC1 (0.51) | NPC1RAB9AKDM4EHSD17B10CASP3 | |
| SCHEMBL2517851 | 0.82 | SELP (0.56) | NPC1RAB9AKDM4EHSD17B10CASP3 | |
| SCHEMBL10362865 | 0.79 | TSHR (0.55) | KDM4EHSD17B10ALDH1A1SMN1; SMN2LTA4H | |
| SCHEMBL14058702 | 0.77 | NPC1 (0.57) | NPC1RAB9AKDM4EHSD17B10CASP3 | |
| SCHEMBL25760380 | 0.76 | CASR (0.74) | NPC1RAB9AKDM4EHSD17B10CASP3 | |
| SCHEMBL14471905 | 0.76 | CASR (0.74) | NPC1RAB9AKDM4EHSD17B10CASP3 | |
| SCHEMBL28447277 | 0.76 | LTA4H (0.49) | LTA4HS1PR1S1PR3 | |
| SCHEMBL11341261 | 0.76 | KDM4E (0.54) | NPC1RAB9AKDM4EHSD17B10CYP2C9 | |
| SCHEMBL177286 | 0.74 | CASR (0.62) | NPC1RAB9AKDM4ESELPSELE | |
| SCHEMBL177287 | 0.74 | CASR (0.62) | NPC1RAB9AKDM4ESELPSELE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345636-A1 | CASR AGONIST | Ajinomoto Co., Inc. (JP) | 2011-07-20 | — | — | EP | disclosed |