Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 8/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740989 | 0.78 | SCN9A (0.38) | SCN9AL3MBTL1ALDH1A1HSD11B1KDM4E | |
| SCHEMBL934639 | 0.78 | SCN9A (0.38) | SCN9AL3MBTL1ALDH1A1HSD11B1KDM4E | |
| SCHEMBL1768310 | 0.76 | TOP1 (0.47) | ALDH1A1KDM4EMAPTPOLBNPSR1 | |
| SCHEMBL7701143 | 0.74 | ALDH1A1 (0.50) | SCN9AL3MBTL1ALDH1A1HSD11B1MPL | |
| SCHEMBL12480202 | 0.73 | MPL (0.44) | SCN9AMPLKDM4ETRPA1CYP2D6 | |
| SCHEMBL24068167 | 0.72 | SCN9A (0.43) | SCN9AL3MBTL1ALDH1A1HSD11B1KDM4E | |
| SCHEMBL14661385 | 0.72 | NOTUM (0.38) | SCN9AL3MBTL1MPLKDM4EMAPT | |
| SCHEMBL1768443 | 0.71 | PDK2 (0.42) | SCN9AL3MBTL1ALDH1A1HSD11B1MPL | |
| SCHEMBL4654446 | 0.71 | RXRA (0.47) | SCN9AL3MBTL1ALDH1A1HSD11B1MPL | |
| SCHEMBL28777064 | 0.69 | SLC22A12 (0.38) | SCN9AL3MBTL1ALDH1A1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061439-A1 | CATALYTIC PHOSPHINATION METHOD | UNIVERSITE DE STRASBOURG (FR) | 2011-05-26 | — | — | WO | disclosed |