Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768452 | 1.00 | GPR119 (0.42) | GPR119CYP2C9CYP2C19PIK3CD | |
| SCHEMBL10170824 | 1.00 | GPR119 (0.42) | GPR119CYP2C9CYP2C19PIK3CD | |
| SCHEMBL13836529 | 0.86 | PIK3CD (0.47) | GPR119PIK3CD | |
| SCHEMBL761206 | 0.86 | PIK3CD (0.47) | GPR119PIK3CD | |
| SCHEMBL288648 | 0.84 | PIK3CD (0.39) | GPR119CYP2C9PIK3CD | |
| SCHEMBL1768128 | 0.84 | PIK3CD (0.39) | GPR119CYP2C9PIK3CD | |
| SCHEMBL298803 | 0.84 | PIK3CD (0.39) | GPR119CYP2C9PIK3CD | |
| SCHEMBL300340 | 0.82 | GPR119 (0.40) | GPR119CYP2C9CYP2C19 | |
| SCHEMBL298847 | 0.82 | GPR119 (0.40) | GPR119CYP2C9CYP2C19 | |
| SCHEMBL759976 | 0.82 | GPR119 (0.40) | GPR119CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061679-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | PFIZER INC. (US) | 2011-05-26 | — | — | WO | disclosed |