Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768128 | 1.00 | PIK3CD (0.39) | PIK3CDTBK1GPR119NTRK1KCNH2 | |
| SCHEMBL288648 | 1.00 | PIK3CD (0.39) | PIK3CDTBK1GPR119NTRK1KCNH2 | |
| SCHEMBL761206 | 0.86 | PIK3CD (0.47) | PIK3CDTBK1GPR119 | |
| SCHEMBL13836529 | 0.86 | PIK3CD (0.47) | PIK3CDTBK1GPR119 | |
| SCHEMBL10170824 | 0.84 | GPR119 (0.42) | PIK3CDGPR119CYP2C9 | |
| SCHEMBL1768452 | 0.84 | GPR119 (0.42) | PIK3CDGPR119CYP2C9 | |
| SCHEMBL1768451 | 0.84 | GPR119 (0.42) | PIK3CDGPR119CYP2C9 | |
| SCHEMBL288925 | 0.81 | GPR119 (0.46) | PIK3CDGPR119CYP2C9 | |
| SCHEMBL14639244 | 0.79 | GPR119 (0.58) | GPR119 | |
| SCHEMBL14637820 | 0.79 | GPR119 (0.58) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427450-A1 | GPR 119 MODULATORS | Pfizer Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| EP-2427448-A1 | Gpr 119 modulators | Pfizer Inc. (US) | 2012-03-14 | — | — | EP | disclosed |