Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 7/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024669 | 0.80 | BMP1 (0.45) | BMP1MMP12 | |
| SCHEMBL6024773 | 0.74 | GNAI3 (0.43) | BMP1MMP12 | |
| SCHEMBL6023832 | 0.73 | BMP1 (0.58) | BMP1MMP12PRSS1 | |
| SCHEMBL6024374 | 0.73 | HPGD (0.52) | BMP1TSHRNPSR1 | |
| SCHEMBL6023825 | 0.73 | BMP1 (0.43) | BMP1MMP12 | |
| SCHEMBL1594895 | 0.73 | MTNR1A (0.47) | BMP1MMP12 | |
| SCHEMBL1594891 | 0.73 | MTNR1A (0.47) | BMP1MMP12 | |
| SCHEMBL1594893 | 0.73 | MTNR1A (0.47) | BMP1MMP12 | |
| SCHEMBL1594888 | 0.73 | MTNR1A (0.47) | BMP1MMP12 | |
| SCHEMBL6024707 | 0.72 | BMP1 (0.56) | BMP1MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363873-B1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2016-04-20 | — | — | EP | claimed |