Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17627114 | 1.00 | MAPT (0.46) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17686769 | 0.85 | CYP1A2 (0.51) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17627132 | 0.85 | CYP1A2 (0.51) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17627139 | 0.78 | MAPT (0.50) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17686765 | 0.78 | MAPT (0.50) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17686768 | 0.73 | ALDH1A1 (0.51) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17627135 | 0.73 | ALDH1A1 (0.51) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12154028 | 0.72 | TACR1 (0.47) | MAPTMEN1KMT2ATACR1LMNA | |
| SCHEMBL12402683 | 0.72 | TACR1 (0.47) | MAPTMEN1KMT2ATACR1LMNA | |
| SCHEMBL12402681 | 0.72 | TACR1 (0.47) | MAPTMEN1KMT2ATACR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999694-B1 | PROCESS FOR PREPARING 3,5-BIS(FLUOROALKYL)PYRAZOLE DERIVATIVES FROM ALPHA,ALPHA -DIHALOAMINES | BAYER CROPSCIENCE AG (DE) | 2017-05-17 | — | — | EP | disclosed |
| US-9512081-B2 | Process for preparing 3,5-bis(fluoroalkyl)pyrazole derivatives from α,α-dihaloamines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-12-06 | — | — | US | disclosed |
| US-20160108000-A1 | PROCESS FOR PREPARING 3,5-BIS(FLUOROALKYL)PYRAZOLE DERIVATIVES FROM a,a-DIHALOAMINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108000-A1 | PROCESS FOR PREPARING 3,5-BIS(FLUOROALKYL)PYRAZOLE DERIVATIVES FROM a,a-DIHALOAMINES | HDHD5, CYP4F3, AADAC | MAPT 2647/4885CYP1A2 53/4885CYP3A4 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.