Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | FURIN | P09958 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17627135 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTCYP2C9CYP1A2CYP3A4 | |
| SCHEMBL2682212 | 0.84 | FURIN (0.58) | ALDH1A1MAPTCYP2C9CYP1A2KMT2A | |
| SCHEMBL17686765 | 0.84 | MAPT (0.50) | ALDH1A1MAPTCYP2C9CYP1A2CYP3A4 | |
| SCHEMBL17627139 | 0.84 | MAPT (0.50) | ALDH1A1MAPTCYP2C9CYP1A2CYP3A4 | |
| SCHEMBL17686769 | 0.81 | CYP1A2 (0.51) | ALDH1A1MAPTCYP2C9CYP1A2CYP3A4 | |
| SCHEMBL17627132 | 0.81 | CYP1A2 (0.51) | ALDH1A1MAPTCYP2C9CYP1A2CYP3A4 | |
| SCHEMBL4037961 | 0.79 | FURIN (0.56) | ALDH1A1MAPTCYP2C9CYP1A2CYP3A4 | |
| SCHEMBL7968589 | 0.79 | FURIN (0.56) | ALDH1A1MAPTCYP2C9CYP1A2CYP3A4 | |
| SCHEMBL4279968 | 0.79 | FURIN (0.56) | ALDH1A1MAPTCYP2C9CYP1A2CYP3A4 | |
| SCHEMBL3272106 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAPTCYP2C9CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408314-B | Process for preparing 3, 5-bis (fluoroalkyl) pyrazole derivatives from α -dihaloamines | 拜耳作物科学股份公司 | 2018-04-24 | — | — | CN | disclosed |
| EP-2999694-B1 | PROCESS FOR PREPARING 3,5-BIS(FLUOROALKYL)PYRAZOLE DERIVATIVES FROM ALPHA,ALPHA -DIHALOAMINES | BAYER CROPSCIENCE AG (DE) | 2017-05-17 | — | — | EP | disclosed |
| US-9512081-B2 | Process for preparing 3,5-bis(fluoroalkyl)pyrazole derivatives from α,α-dihaloamines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-12-06 | — | — | US | disclosed |
| US-20160108000-A1 | PROCESS FOR PREPARING 3,5-BIS(FLUOROALKYL)PYRAZOLE DERIVATIVES FROM a,a-DIHALOAMINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-04-21 | — | — | US | disclosed |
| CN-105408314-A | Process for preparing 3, 5-bis (fluoroalkyl) pyrazole derivatives from alpha, alpha-dihaloamines | BAYER CROPSCIENCE AG | 2016-03-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108000-A1 | PROCESS FOR PREPARING 3,5-BIS(FLUOROALKYL)PYRAZOLE DERIVATIVES FROM a,a-DIHALOAMINES | HDHD5, CYP4F3, AADAC | ALDH1A1 308/4885MAPT 2647/4885CYP2C9 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.