SCHEMBL4279968

SCHEMBL4279968

CC(=NN=C(C)c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FURIN P09958 2/20 0.56
LMNA P02545 3/20 0.54
MAPK1 P28482 1/20 0.54
HTT P42858 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
MAPT P10636 3/20 0.52
CYP1A2 P05177 2/20 0.52
CYP2D6 P10635 2/20 0.52
POLB P06746 2/20 0.52
HSD17B10 Q99714 1/20 0.52
NPC1 O15118 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
RAB9A P51151 2/20 0.50
ALDH1A1 P00352 3/20 0.48
KMT2A Q03164 2/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
RECQL P46063 1/20 0.48
ATM Q13315 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7968589 1.00 FURIN (0.56) FURINLMNAMAPK1HTTL3MBTL1
SCHEMBL4037961 1.00 FURIN (0.56) FURINLMNAMAPK1HTTL3MBTL1
SCHEMBL21239899 0.92 FURIN (0.50) FURINLMNAMAPK1HTTL3MBTL1
2-(1-Phenylethylidene)Hydrazinecarboximidamide SCHEMBL12217973 0.88 FURIN (0.78) FURINLMNAMAPK1HTTL3MBTL1
SCHEMBL10802869 0.88 CES2 (0.56) FURINLMNAMAPK1HTTL3MBTL1
SCHEMBL12217988 0.88 FURIN (0.58) FURINLMNAMAPK1HTTL3MBTL1
SCHEMBL27453647 0.88 FURIN (0.46) FURINLMNAMAPK1HTTL3MBTL1
SCHEMBL45278 0.80 LMNA (0.52) LMNAMAPK1HTTL3MBTL1MAPT
SCHEMBL2736631 0.80 LMNA (0.52) LMNAMAPK1HTTL3MBTL1MAPT
SCHEMBL3443700 0.80 LMNA (0.52) LMNAMAPK1HTTL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113933425-B Method for measuring content of acetophenone azine in plastic, chloroprene rubber or foam 通标标准技术服务(上海)有限公司 2024-06-21 CN claimed
CN-113933425-A Method for measuring content of acetophenone azine in plastic, chloroprene rubber and foam 通标标准技术服务(上海)有限公司 2022-01-14 CN claimed
JP-4341191-A None JP disclosed
CN-113933425-B Method for measuring content of acetophenone azine in plastic, chloroprene rubber or foam 通标标准技术服务(上海)有限公司 2024-06-21 CN disclosed
CN-113933425-B Method for measuring content of acetophenone azine in plastic, chloroprene rubber or foam 通标标准技术服务(上海)有限公司 2024-06-21 CN disclosed
CN-113933425-B Method for measuring content of acetophenone azine in plastic, chloroprene rubber or foam 通标标准技术服务(上海)有限公司 2024-06-21 CN disclosed
CN-113933425-A Method for measuring content of acetophenone azine in plastic, chloroprene rubber and foam 通标标准技术服务(上海)有限公司 2022-01-14 CN disclosed
CN-113933425-A Method for measuring content of acetophenone azine in plastic, chloroprene rubber and foam 通标标准技术服务(上海)有限公司 2022-01-14 CN disclosed
EP-2598946-B1 POLYMERIZABLE COMPOSITION FUJIFILM CORP (JP) 2019-04-03 EP disclosed
CN-105566227-B It is a kind of to close the nitrogen activation and method for transformation that object promotes by bivalent rare earth iodine 复旦大学 2019-01-15 CN disclosed
US-8895306-B2 Oxadiazoline ligands for modulating the expression of exogenous genes via an ecdysone receptor complex INTREXON CORPORATION (US) 2014-11-25 US disclosed
US-7034184-B2 Process for producing azine compounds and oxime compounds DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-04-25 US disclosed
EP-1342714-B1 Process for producing azine compounds and oxime compounds DAICEL CHEM (JP) 2005-01-26 EP disclosed
US-20040171651-A1 Regulating and tailoring expression levels; such as N-[3-(4-chloro-phenyl)-5,5-dimethyl-[1,2,4]oxadiazol-4-yl]-3-ethyl-benzamide RHEOGENE, INC. (DE CORPORATION) 2004-09-02 US disclosed
US-20030204084-A1 Process for producing azine compounds and oxime compounds DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-10-30 US disclosed
EP-1342714-A1 Process for producing azine compounds and oxime compounds Daicel Chemical Industries, Ltd. (JP) 2003-09-10 EP disclosed
US-6229047-B1 NONLINEAR OPTICAL MATERIAL WHICH IS CHARACTERIZED AS HAVING A HIGH MACROSCOPIC DIPOLE MOMENT ACHIEVED THROUGH PARALLEL PACKING OF DIPOLAR MOLECULES (CRYSTALLINE AZINE BRIDGED DI-ARENE) THE CURATORS OF THE UNIVERSITY OF MISSOURI 2001-05-08 US disclosed
EP-0273274-B1 Degradation of polyethylene by means of agents generating free radicals ATOCHEM ELF DEUTSCHLAND (DE) 2000-07-12 EP disclosed
JP-H04341191-A PRODUCTION OF OPTICALLY ACTIVE ALPHA-METHYLBENZYLAMINE MERCIAN CORP 1992-11-27 JP disclosed
US-3972876-A Process for the preparation of symmetrical and unsymmetrical azines and mixtures thereof PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030204084-A1 Process for producing azine compounds and oxime compounds CBR1, DAO, ALKBH2 FURIN 4064/4885LMNA 3050/4885MAPK1 1839/4885
US-20040171651-A1 Regulating and tailoring expression levels; such as N-[3-(4-chloro-phenyl)-5,5-dimethyl-[1,2,4]oxadiazol-4-yl]-3-ethyl-benzamide NR2E3, ESRRB, NR0B2 FURIN 4130/4885LMNA 2416/4885MAPK1 3918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.