SCHEMBL1768835

SCHEMBL1768835

CC(=O)NCC[C@H](N)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.48
MTNR1B P49286 1/20 0.48
GSR P00390 2/20 0.46
CYP1A2 P05177 2/20 0.46
GRM8 O00222 1/20 0.46
GRM6 O15303 1/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIK1 P39086 1/20 0.46
GRM5 P41594 1/20 0.46
GRIA1 P42261 1/20 0.46
GRIA2 P42262 1/20 0.46
GRIA3 P42263 1/20 0.46
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
GRIA4 P48058 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIK2 Q13002 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22776394 1.00 MTNR1A (0.48) MTNR1AMTNR1BGSRCYP1A2GRM8
SCHEMBL1512848 1.00 MTNR1A (0.48) MTNR1AMTNR1BGSRCYP1A2GRM8
SCHEMBL22776508 1.00 MTNR1A (0.48) MTNR1AMTNR1BGSRCYP1A2GRM8
SCHEMBL1768663 0.92 MTNR1A (0.43) MTNR1AMTNR1BGSRCYP1A2GRM8
SCHEMBL1768665 0.92 MTNR1A (0.43) MTNR1AMTNR1BGSRCYP1A2GRM8
SCHEMBL2238055 0.88 OTC (0.57) GSRCYP1A2KMT2ABLMKDM4E
SCHEMBL3503365 0.88 OTC (0.57) GSRCYP1A2KMT2ABLMKDM4E
SCHEMBL976174 0.88 OTC (0.57) GSRCYP1A2KMT2ABLMKDM4E
SCHEMBL180969 0.86 KDM4E (0.56) GSRCYP1A2KMT2ABLMKDM4E
SCHEMBL236178 0.86 KDM4E (0.56) GSRCYP1A2KMT2ABLMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116921-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS INC (US) 2026-04-30 US claimed
EP-4720086-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Zealand Pharma A/S (DK) 2026-04-08 EP claimed
EP-4720087-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Zealand Pharma A/S (DK) 2026-04-08 EP claimed
EP-4658374-A1 METHODS FOR PREPARING CRYSTALLINE PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Janssen Pharmaceutica NV (BE) 2025-12-10 EP claimed
EP-4613761-A9 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES Janssen Biotech, Inc. (US) 2025-10-22 EP claimed
EP-4622991-A2 SYNTHESIS OF A CYCLIC PEPTIDE Janssen Pharmaceutica NV (BE) 2025-10-01 EP claimed
EP-4613761-A2 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES Janssen Biotech, Inc. (US) 2025-09-10 EP claimed
WO-2025073222-A1 GLP-1R/GIPR/GCGR TRIPLE AGONIST ANALOGUE AND USE THEREOF 深圳湾实验室 2025-04-10 WO claimed
WO-2024246268-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR ZEALAND PHARMA A/S (DK) 2024-12-05 WO claimed
WO-2024246269-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR ZEALAND PHARMA A/S (DK) 2024-12-05 WO claimed
US-20220251142-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS, INC. 2022-08-11 US claimed
EP-3997105-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES Protagonist Therapeutics, Inc. (US) 2022-05-18 EP claimed
US-20220125885-A1 GLUCAGON ANALOG AGONISTS AND METHODS OF USING THE SAME ELI LILLY AND COMPANY 2022-04-28 US claimed
CN-114341161-A Peptide inhibitors of interleukin-23 receptor and their use for the treatment of inflammatory diseases 领导医疗有限公司 2022-04-12 CN claimed
US-20220041658-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS, INC. 2022-02-10 US claimed
US-20210147889-A1 METHOD FOR ENHANCING CONTINUOUS PRODUCTION OF A NATURAL COMPOUND DURING EXPONENTIAL GROWTH PHASE AND STATIONARY PHASE OF A MICROORGANISM Bundesrepublik Deutschland, vertreten durch die Bundesministerin für Wirtschaft und Energie (DE) 2021-05-20 US claimed
CN-112342202-B Tetrahydromethylpyrimidine carboxylic acid biosynthesis gene and application thereof 江苏省中国科学院植物研究所 2021-04-27 CN claimed
CN-112342202-A Tetrahydromethylpyrimidine carboxylic acid biosynthesis gene and application thereof 江苏省中国科学院植物研究所 2021-02-09 CN claimed
WO-2020250855-A1 CYCLIC PEPTIDE, CELL SCAFFOLD MATERIAL, CELL SEPARATION MATERIAL AND CULTURE MEDIUM 富士フイルム株式会社 2020-12-17 WO claimed
EP-3608404-A1 AN IMPROVED METHOD TO PRODUCE CHEMICAL COMPOUNDS DERIVED FROM OXALOACETATE BY MICROORGANISMS Technische Universität München (DE) 2020-02-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220251142-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, VIP MTNR1A 811/4885MTNR1B 960/4885GSR 3905/4885
US-20220125885-A1 GLUCAGON ANALOG AGONISTS AND METHODS OF USING THE SAME GLP1R, GCG, GCGR MTNR1A 570/4885MTNR1B 538/4885GSR 564/4885
US-20220041658-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, VIP MTNR1A 811/4885MTNR1B 960/4885GSR 3905/4885
US-20260116921-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, IL36G MTNR1A 45/4885MTNR1B 94/4885GSR 3713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.