Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1657403 | 0.81 | NPSR1 (0.39) | POLBALDH1A1TDP1L3MBTL1KMT2A | |
| SCHEMBL11568673 | 0.81 | MAPT (0.35) | ALDH1A1TDP1L3MBTL1RORCKMT2A | |
| SCHEMBL9784429 | 0.80 | PDK1 (0.34) | POLBALDH1A1TDP1L3MBTL1RORC | |
| SCHEMBL4147870 | 0.77 | MAPK1 (0.44) | POLBALDH1A1KMT2AGAAMEN1 | |
| Nitric Acid SCHEMBL20984720 | 0.77 | POLB (0.70) | POLBALDH1A1TDP1L3MBTL1RORC | |
| SCHEMBL6852072 | 0.74 | RAB9A (0.47) | POLBALDH1A1TDP1L3MBTL1RORC | |
| SCHEMBL11571266 | 0.73 | GAA (0.47) | ALDH1A1L3MBTL1GAAAKR1C3AKR1C2 | |
| SCHEMBL23581575 | 0.72 | POLB (0.64) | POLBALDH1A1TDP1L3MBTL1KMT2A | |
| SCHEMBL395435 | 0.72 | ALDH1A1 (0.64) | POLBALDH1A1TDP1L3MBTL1KMT2A | |
| Nitric Acid SCHEMBL6033278 | 0.72 | ALDH1A1 (0.49) | POLBALDH1A1TDP1L3MBTL1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058577-A1 | PROCESS FOR SYNTHESIZING POLYHALOGENATED PERHALOALKYLANILINE COMPOUNDS | GHARDA KEKI HORMUSJI (IN) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011058576-A1 | PROCESS FOR PREPARING POLYHALOGENATED PERHALOALKYLANILINE | GHARDA KEKI HORMUSJI (IN) | 2011-05-19 | — | — | WO | disclosed |
| EP-1848713-A2 | AMIDE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006053778-A2 | AMIDE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-05-26 | — | — | WO | disclosed |
| EP-0381010-A3 | PROCESS FOR THE PREPARATION OF 2-NITRO-4-TRIFLUOROMETHYL ANILINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-17 | — | — | EP | disclosed |
| EP-0381010-A2 | Process for the preparation of 2-nitro-4-trifluoromethyl aniline | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-08 | — | — | EP | disclosed |
| EP-0280156-A2 | Process for the preparation of acetoacetylarylamides-heteroarylamides respectively of deactived aromatic compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-31 | — | — | EP | disclosed |
| US-4096185-A | P-CHLOROBENZOTRIFLUORIDE, AMMONIA, COPPER COMPOUND CATALYST | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-06-20 | — | — | US | disclosed |