Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.80 |
| ▸ | MAPT | P10636 | 5/20 | 0.80 |
| ▸ | POLB | P06746 | 5/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.80 |
| ▸ | BLM | P54132 | 3/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.80 |
| ▸ | RECQL | P46063 | 2/20 | 0.80 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.80 |
| ▸ | PKM | P14618 | 2/20 | 0.80 |
| ▸ | USP2 | O75604 | 1/20 | 0.80 |
| ▸ | THRB | P10828 | 1/20 | 0.80 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | APEX1 | P27695 | 1/20 | 0.77 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17689183 | 0.80 | MAPT (0.69) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL15113174 | 0.79 | ALDH1A1 (0.78) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL13253495 | 0.75 | MEN1 (0.56) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL20014209 | 0.73 | CTDSP1 (0.61) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL20013858 | 0.73 | CTDSP1 (0.65) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL17681382 | 0.73 | MAPT (0.82) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL17689201 | 0.69 | MEN1 (0.73) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL13253500 | 0.69 | CHEK1 (0.59) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL1899815 | 0.69 | STAT3 (1.00) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL17681381 | 0.68 | MAPT (0.79) | ALDH1A1KDM4EMAPTPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10350225-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | NANT HOLDINGS IP, LLC (US) | 2019-07-16 | — | — | US | disclosed |
| US-9315464-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | NANT HOLDINGS IP, LLC (US) | 2016-04-19 | — | — | US | disclosed |
| US-9315464-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | NANT HOLDINGS IP, LLC (US) | 2016-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10350225-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | RNGTT, MED23, MED25 | ALDH1A1 3512/4885KDM4E 1204/4885MAPT 2791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.