Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | CNR1 | P21554 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17681382 | 0.92 | MAPT (0.82) | MAPTKDM4ELMNAL3MBTL1CYP2C9 | |
| SCHEMBL17689198 | 0.80 | ALDH1A1 (0.80) | MAPTKDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL17689217 | 0.78 | MAPT (0.86) | MAPTKDM4ELMNAL3MBTL1CYP2C9 | |
| SCHEMBL20014197 | 0.78 | CYP2C9 (0.75) | MAPTKDM4ELMNAL3MBTL1CYP2C9 | |
| SCHEMBL17681381 | 0.75 | MAPT (0.79) | MAPTKDM4ELMNACYP2C9ALDH1A1 | |
| SCHEMBL15452447 | 0.74 | CYP3A4 (0.84) | MAPTL3MBTL1CYP2C9ALDH1A1MEN1 | |
| SCHEMBL17689204 | 0.74 | CYP2C9 (0.80) | MAPTKDM4ELMNAL3MBTL1CYP2C9 | |
| SCHEMBL17681383 | 0.74 | MEN1 (1.00) | MAPTKDM4ELMNAL3MBTL1CYP2C9 | |
| SCHEMBL17689185 | 0.73 | MEN1 (0.76) | MAPTKDM4ELMNACYP2C9ALDH1A1 | |
| SCHEMBL17681384 | 0.72 | MEN1 (1.00) | MAPTKDM4ELMNAL3MBTL1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10350225-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | NANT HOLDINGS IP, LLC (US) | 2019-07-16 | — | — | US | disclosed |
| US-9315464-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | NANT HOLDINGS IP, LLC (US) | 2016-04-19 | — | — | US | disclosed |
| US-9315464-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | NANT HOLDINGS IP, LLC (US) | 2016-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10350225-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | RNGTT, MED23, MED25 | MAPT 2791/4885KDM4E 1204/4885LMNA 3151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.