Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197516 | 0.78 | ALDH1A1 (0.41) | TDP1FBP1ALDH1A1TSHRAKR1C3 | |
| Hydrochloric Acid SCHEMBL5256199 | 0.76 | ALDH1A1 (0.39) | TDP1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL13461939 | 0.75 | HSD17B10 (0.42) | FBP1ALDH1A1G6PDMAOBCYP2A6 | |
| SCHEMBL18040865 | 0.74 | G6PD (0.47) | TDP1FBP1ALDH1A1TSHRG6PD | |
| SCHEMBL10448311 | 0.74 | G6PD (0.47) | TDP1FBP1ALDH1A1TSHRG6PD | |
| SCHEMBL1404289 | 0.74 | G6PD (0.47) | TDP1FBP1ALDH1A1TSHRG6PD | |
| SCHEMBL22575907 | 0.74 | G6PD (0.47) | TDP1FBP1ALDH1A1TSHRG6PD | |
| SCHEMBL14304177 | 0.73 | TDP1 (0.46) | TDP1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL17086575 | 0.73 | TDP1 (0.46) | TDP1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL19217996 | 0.72 | ALDH1A1 (0.41) | TDP1ALDH1A1TSHRG6PDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621905-B1 | METHODS INCLUDING LATENT 1,3-DIPOLE-FUNCTIONAL COMPOUNDS AND MATERIALS PREPARED THEREBY | UNIV GEORGIA (US) | 2017-04-12 | — | — | EP | disclosed |
| US-9315468-B2 | Methods including latent 1,3-dipole-functional compounds and materials prepared thereby | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2016-04-19 | — | — | US | disclosed |