Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHAT | P28329 | 2/20 | 0.37 |
| ▸ | FBP1 | P09467 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5256199 | 0.97 | ALDH1A1 (0.39) | ALDH1A1TSHRMAOBCYP2A6G6PD | |
| SCHEMBL22575907 | 0.78 | G6PD (0.47) | ALDH1A1TSHRG6PDPOLBGAA | |
| SCHEMBL10448311 | 0.78 | G6PD (0.47) | ALDH1A1TSHRG6PDPOLBGAA | |
| SCHEMBL17689681 | 0.78 | TDP1 (0.41) | ALDH1A1TSHRMAOBCYP2A6G6PD | |
| SCHEMBL1404289 | 0.78 | G6PD (0.47) | ALDH1A1TSHRG6PDPOLBGAA | |
| SCHEMBL27493057 | 0.74 | CYP2A6 (0.48) | ALDH1A1CYP2A6POLBTDP1L3MBTL1 | |
| SCHEMBL17083888 | 0.74 | TDP1 (0.43) | ALDH1A1TSHRMAOBCYP2A6G6PD | |
| SCHEMBL14633792 | 0.74 | TDP1 (0.43) | ALDH1A1TSHRMAOBCYP2A6G6PD | |
| SCHEMBL22728584 | 0.74 | RELA (0.36) | ALDH1A1TSHRMAOBCYP2A6G6PD | |
| SCHEMBL27559085 | 0.72 | TP53 (0.56) | ALDH1A1TSHRMAOBTDP1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11982395-B2 | Insulated pipe containing polyurethane foam which is foamed by an environmentally friendly foaming agent and has a low degree of brittleness | BASF SE (DE) | 2024-05-14 | — | — | US | disclosed |
| EP-3947501-B1 | INSULATED PIPE, COMPRISING AN ENVIRONMENTALLY-FRIENDLY PROPELLANT BLOWN POLYURETHANE FOAM WITH LOW FRIABILITY | BASF SE (DE) | 2023-07-12 | — | — | EP | disclosed |
| US-20220163162-A1 | INSULATED PIPE CONTAINING POLYURETHANE FOAM WHICH IS FOAMED BY AN ENVIRONMENTALLY FRIENDLY FOAMING AGENT AND HAS A LOW DEGREE OF BRITTLENESS | BASF SE (DE) | 2022-05-26 | — | — | US | disclosed |
| CN-1247542-C | Substituted pyrrole Mannich bases to treating paint and allergic reactions | GREENTHAL GMBH (DE) | 2006-03-29 | — | — | CN | disclosed |
| US-6584671-B2 | Simple, low cost manufacturing of strong, weather resistant assembly | THYSSEN TRANSRAPID SYSTEM GMBH (DE) | 2003-07-01 | — | — | US | disclosed |
| CN-1414950-A | Substituted pyrrole mannich bases for the treatment of pain and hypersensitivity reactions | GREENTHAL GMBH (DE) | 2003-04-30 | — | — | CN | disclosed |
| CN-1413185-A | Substitued 1 and 2 naphthol mannich bases | GRUENENTHAL GMBH (DE) | 2003-04-23 | — | — | CN | disclosed |
| CN-1413192-A | Substituted indole mannich bases | GRUENENTHAL GMBH (DE) | 2003-04-23 | — | — | CN | disclosed |
| EP-1253917-A2 | USE OF SUBSTITUTED 4-AMINO-1-PHENYLBUTAN-2-OL COMPOUNDS AS MEDICAMENTS | Grünenthal GmbH (DE) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001047506-A2 | USE OF SUBSTITUTED 4-AMINO-1-PHENYLBUTAN-2-OL COMPOUNDS AS MEDICAMENTS | Grünenthal GmbH (DE) | 2001-07-05 | — | — | WO | disclosed |
| US-20010002507-A1 | PROCESS FOR PRODUCING AN ELECTROMAGNETIC SUBASSEMBLY FOR A MAGNETIC LEVITATION RAILWAY | THYSSEN TRANSRAPID SYSTEM GMBH (DE) | 2001-06-07 | — | — | US | disclosed |
| US-4933265-A | NUCLEATION PROMOTER | FUJI PHOTO FILM CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| US-4073767-A | Hydrogen phosphonates and polymers containing them as flame retardants | MONSANTO COMPANY (US) | 1978-02-14 | — | — | US | disclosed |