Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241977 | 0.79 | MAPK1 (0.60) | MKNK1MKNK2GLO1PHLPP2TDP1 | |
| SCHEMBL17340268 | 0.79 | KMT2A (0.47) | MKNK1MKNK2NNMTKDM4EALDH1A1 | |
| SCHEMBL28253687 | 0.76 | MKNK1 (0.40) | MKNK1MKNK2NOS1TDP1SIRT3 | |
| SCHEMBL17340297 | 0.76 | HPGD (0.48) | ALDH1A1GAAKMT2A | |
| SCHEMBL7888202 | 0.74 | ALDH1A1 (0.42) | GLO1TDP1KDM4EALDH1A1GAA | |
| SCHEMBL31702340 | 0.73 | KMT2A (0.57) | GLO1PHLPP2TDP1KDM4EALDH1A1 | |
| SCHEMBL2128609 | 0.72 | PARP1 (0.52) | MKNK1MKNK2BRD4TDP1SIRT3 | |
| SCHEMBL284479 | 0.72 | MKNK1 (0.49) | MKNK1MKNK2TDP1SIRT3NNMT | |
| SCHEMBL17857332 | 0.71 | CYP3A4 (0.59) | GLO1PHLPP2TDP1KDM4EALDH1A1 | |
| SCHEMBL1095966 | 0.71 | ALDH1A1 (0.50) | MKNK1MKNK2TDP1SIRT3NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428508-B9 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | ASTELLAS PHARMA INC (JP) | 2016-04-20 | — | — | EP | disclosed |